Interleukin 2 high-affinity receptor expression requires two distinct binding proteins.
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Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodiesExpression cloning of a receptor for human granulocyte-macrophage colony-stimulating factorHuman IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunityMedical immunology: a new journal for a new subspecialty.Human interleukin 2 receptor beta-chain gene: chromosomal localization and identification of 5' regulatory sequencesBY55 monoclonal antibody delineates within human cord blood and bone marrow lymphocytes distinct cell subsets mediating cytotoxic activityThe integrity of the conserved 'WS motif' common to IL-2 and other cytokine receptors is essential for ligand binding and signal transductionThe quantal theory of how the immune system discriminates between "self and non-self"Human thymic epithelial cells directly induce activation of autologous immature thymocytes.Regulation of interleukin 2 receptor alpha subunit (Tac or CD25 antigen) gene expression: binding of inducible nuclear proteins to discrete promoter sequences correlates with transcriptional activation.Generation of lymphokine-activated killer cells: synergy between tumor necrosis factor and interleukin 2A 100-kilodalton protein is associated with the murine interleukin 2 receptor: biochemical evidence that p100 is distinct from the alpha and beta chainsInterleukin 2 receptor beta chain expressed in an oligodendroglioma line binds interleukin 2 and delivers growth signalMitogenicity and down-regulation of high-affinity interleukin 2 receptor by YTA-1 and YTA-2, monoclonal antibodies that recognize 75-kDa molecules on human large granular lymphocytes.Tumor necrosis factor alpha induces proteins that bind specifically to kappa B-like enhancer elements and regulate interleukin 2 receptor alpha-chain gene expression in primary human T lymphocytes.Stat1 and Stat2 but not Stat3 arbitrate contradictory growth signals elicited by alpha/beta interferon in T lymphocytes.The first alpha helix of interleukin (IL)-2 folds as a homotetramer, acts as an agonist of the IL-2 receptor beta chain, and induces lymphokine-activated killer cellsMurine interleukin 2 receptor beta chain: dysregulated gene expression in lymphoma line EL-4 caused by a promoter insertionRegulation of interleukin 2-dependent growth responses by glycosylphosphatidylinositol molecules.Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association.Production of granulocyte/macrophage-colony-stimulating factor by human natural killer cells. Modulation by the p75 subunit of the interleukin 2 receptor and by the CD2 receptor.Suppression of interleukin 2-dependent human T cell growth in vitro by prostaglandin E (PGE) and their precursor fatty acids. Evidence for a PGE-independent mechanism of inhibition by the fatty acidsInability of mitogen-activated lymphocytes obtained from patients with malignant primary intracranial tumors to express high affinity interleukin 2 receptors.Differential regulation of lymphokine production by distinct subunits of the T cell interleukin 2 receptorThe same 50-kDa cellular protein binds to the negative regulatory elements of the interleukin 2 receptor alpha-chain gene and the human immunodeficiency virus type 1 long terminal repeatCoordinated action of IgE and a B-cell-stimulatory factor on the CD23 receptor molecule up-regulates B-lymphocyte growth.Increased concentrations of interleukin 1 beta, interleukin-2, and soluble interleukin-2 receptors in endoscopical mucosal biopsy specimens with active inflammatory bowel diseasePlasma interleukin-2 and a soluble/shed interleukin-2 receptor in serum of patients with Crohn's disease. Effect of cyclosporin.Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor.Spontaneous expression of the interleukin 2 receptor gene and presence of functional interleukin 2 receptors on T lymphocytes in the blood of individuals with active pulmonary sarcoidosisInterleukin 2 binding molecule distinct from the Tac protein: analysis of its role in formation of high-affinity receptors.Contribution of a p75 interleukin 2 binding peptide to a high-affinity interleukin 2 receptor complexThe interleukin 2 receptor in the hypereosinophilic syndrome.Cytokines in inflammatory bowel disease.Novel interleukin 2 (IL-2) receptor appears to mediate IL-2-induced activation of natural killer cells.Interleukin-2 receptor-directed immunosuppressive therapies: antibody- or cytokine-based targeting molecules.Human NK cells in health and disease: clinical, functional, phenotypic and DNA genotypic characteristics.Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donorsLymphocytes expressing type 3 complement receptors proliferate in response to interleukin 2 and are the precursors of lymphokine-activated killer cells.In vivo administration of azithromycin affects lymphocyte activity in vitro.
P2860
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P2860
Interleukin 2 high-affinity receptor expression requires two distinct binding proteins.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
1987年學術文章
@zh
1987年學術文章
@zh-hant
name
Interleukin 2 high-affinity receptor expression requires two distinct binding proteins.
@ast
Interleukin 2 high-affinity receptor expression requires two distinct binding proteins.
@en
type
label
Interleukin 2 high-affinity receptor expression requires two distinct binding proteins.
@ast
Interleukin 2 high-affinity receptor expression requires two distinct binding proteins.
@en
prefLabel
Interleukin 2 high-affinity receptor expression requires two distinct binding proteins.
@ast
Interleukin 2 high-affinity receptor expression requires two distinct binding proteins.
@en
P2093
P2860
P356
P1476
Interleukin 2 high-affinity receptor expression requires two distinct binding proteins.
@en
P2093
P2860
P304
P356
10.1084/JEM.165.1.223
P407
P577
1987-01-01T00:00:00Z