Perforin and serine esterase gene expression in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A
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Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11Differential effects of IL-21 and IL-15 on perforin expression, lysosomal degranulation, and proliferation in CD8 T cells of patients with human immunodeficiency virus-1 (HIV)A comparative study of the expression of cytotoxic proteins in allergic contact dermatitis and psoriasis: spongiotic skin lesions in allergic contact dermatitis are highly infiltrated by T cells expressing perforin and granzyme BGranzyme A and B-deficient killer lymphocytes are defective in eliciting DNA fragmentation but retain potent in vivo anti-tumor capacity.Expression, processing and transcriptional regulation of granulysin in short-term activated human lymphocytes.Quantitative fluorescence measures for determination of intracellular perforin content.Discordant regulation of granzyme H and granzyme B expression in human lymphocytes.Death by a thousand cuts: granzyme pathways of programmed cell deathIn situ cDNA polymerase chain reaction. A novel technique for detecting mRNA expression.Rational immunotherapy with interleukin 2.Granzyme B expression in Reed-Sternberg cells of Hodgkin's disease.High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability.Primary cutaneous CD8-positive epidermotropic cytotoxic T cell lymphomas. A distinct clinicopathological entity with an aggressive clinical behavior.Perforin mRNA expression in the inflamed tissues of NZB/W F1 lupus mice decreases with methylprednisolone treatmentExpression of cytolytic mediators by synovial fluid lymphocytes in rheumatoid arthritis.Immunohistochemical identification of cytotoxic lymphocytes using human perforin monoclonal antibodyIn situ detection of activated cytotoxic cells in follicular lymphomas.Live cell evaluation of granzyme delivery and death receptor signaling in tumor cells targeted by human natural killer cellsGenomic organization of the mouse pore-forming protein (perforin) gene and localization to chromosome 10. Similarities to and differences from C9.Interleukin 2 receptor signaling regulates the perforin gene through signal transducer and activator of transcription (Stat)5 activation of two enhancersExpression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte-induced apoptosis: differential modulation by T helper type 1 and type 2 cells.The involvement of interleukin (IL)-15 in regulating the differentiation of granulated metrial gland cells in mouse pregnant uterus.Permanent CD8(+) T cell depletion prevents proteinuria in active Heymann nephritis.Assessment of cytotoxic T-lymphocyte phenotype using the specific markers granzyme B and TIA-1 in cervical neoplastic lesions.The transcriptional control of the perforin locusTarget cell death triggered by cytotoxic T lymphocytes: a target cell mutant distinguishes passive pore formation and active cell suicide mechanismsPerforin and granzyme A expression identifying cytolytic lymphocytes in rheumatoid arthritisDifferential expression of perforin in muscle-infiltrating T cells in polymyositis and dermatomyositisIdentification of a killer cell-specific regulatory element of the mouse perforin gene: an Ets-binding site-homologous motif that interacts with Ets-related proteins.PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cellsExpression of T-cell-associated serine proteinase 1 during murine Leishmania major infection correlates with susceptibility to disease.Perforin/granzyme-dependent and independent mechanisms are both important for the development of graft-versus-host disease after murine bone marrow transplantationChildhood mycosis fungoides with a CD8+ CD56+ cytotoxic immunophenotype.Ikaros imposes a barrier to CD8+ T cell differentiation by restricting autocrine IL-2 production.Nonspecific immune responses and mechanisms of resistance to Eimeria papillata infections in mice.Perforin and lymphocyte-mediated cytolysis.Analysis of perforin expression in human peripheral blood lymphocytes, CD56+ natural killer cell subsets and its induction by interleukin-2.Expression of perforin and serine esterases by human gamma/delta T cells.T cell receptor-zeta and granzyme B expression in mononuclear cell infiltrates in normal colon mucosa and colon carcinoma.The CD8+ granzyme B+ T-cell subset in peripheral blood from healthy individuals contains activated and apoptosis-prone cells.
P2860
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P2860
Perforin and serine esterase gene expression in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh
1989年學術文章
@zh-hant
name
Perforin and serine esterase g ...... , and effects of cyclosporin A
@ast
Perforin and serine esterase g ...... , and effects of cyclosporin A
@en
type
label
Perforin and serine esterase g ...... , and effects of cyclosporin A
@ast
Perforin and serine esterase g ...... , and effects of cyclosporin A
@en
prefLabel
Perforin and serine esterase g ...... , and effects of cyclosporin A
@ast
Perforin and serine esterase g ...... , and effects of cyclosporin A
@en
P2093
P2860
P356
P1476
Perforin and serine esterase g ...... , and effects of cyclosporin A
@en
P2093
A Granelli-Piperno
J A Trapani
P2860
P304
P356
10.1084/JEM.170.6.2105
P407
P577
1989-12-01T00:00:00Z