T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus - Test2 - elhamkhani - TriplyDB

T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus

T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus

http://www.wikidata.org/entity/Q36364979

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Systemic Lupus Erythematosus: Molecular Mimicry between Anti-dsDNA CDR3 Idiotype, Microbial and Self Peptides-As Antigens for Th Cells Somatic mutagenesis in autoimmunity Amphipathic variable region heavy chain peptides derived from monoclonal human Wegener's anti-PR3 antibodies stimulate lymphocytes from patients with Wegener's granulomatosis and microscopic polyangiitis Blockade of programmed death-1 in young (New Zealand Black x New Zealand White)F1 mice promotes the suppressive capacity of CD4+ regulatory T cells protecting from lupus-like disease Spontaneous autoimmunity in mice that carry an IghV partial transgene: a required arginine in VHCDR3.Environmentally induced autoimmune diseases: potential mechanisms T cell hyperactivity in lupus as a consequence of hyperstimulatory antigen-presenting cells.Pathogenesis of systemic lupus erythematosus (SLE).Invariant NKT cells inhibit autoreactive B cells in a contact- and CD1d-dependent manner.The role of VH determinants in systemic lupus erythematosus.Invariant natural killer T cells in lupus patients promote IgG and IgG autoantibody production.Aborted germinal center reactions and B cell memory by follicular T cells specific for a B cell receptor V region peptide.Inhibition of BTK and ITK with Ibrutinib Is Effective in the Prevention of Chronic Graft-versus-Host Disease in Mice Immune tolerance to autoantibody-derived peptides delays development of autoimmunity in murine lupus.BLyS antagonists and peptide tolerance induction.Modulation of murine systemic lupus erythematosus with peptides based on complementarity determining regions of a pathogenic anti-DNA monoclonal antibody.SLE: translating lessons from model systems to human disease Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus Neonatal peptide exposure can prime T cells and, upon subsequent immunization, induce their immune deviation: implications for antibody vs. T cell-mediated autoimmunity.Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus Vaccination with minigenes encoding V(H)-derived major histocompatibility complex class I-binding epitopes activates cytotoxic T cells that ablate autoantibody-producing B cells and inhibit lupus.Subsets of transgenic T cells that recognize CD1 induce or prevent murine lupus: role of cytokines.Activation and tolerance in CD4(+) T cells reactive to an immunoglobulin variable region.Regulatory T cells in lupus.The natural killer T cell ligand alpha-galactosylceramide prevents or promotes pristane-induced lupus in mice Differences between CD8+ T cells in lupus-prone (NZB x NZW) F1 mice and healthy (BALB/c x NZW) F1 mice may influence autoimmunity in the lupus model.Examining the role of CD1d and natural killer T cells in the development of nephritis in a genetically susceptible lupus model Differential contribution of IL-4 and STAT6 vs STAT4 to the development of lupus nephritis.Germline deletion of β2 microglobulin or CD1d reduces anti-phospholipid antibody, but increases autoantibodies against non-phospholipid antigens in the NZB/W F1 model of lupus Leptin promotes systemic lupus erythematosus by increasing autoantibody production and inhibiting immune regulation Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production.Evidence for multiple mechanisms of polyclonal T cell activation in murine lupus.Regulatory T cells in immune-mediated renal disease.Activation of diverse repertoires of autoreactive T cells enhances the loss of anti-dsDNA B cell tolerance.Autoreactive human T cell lines recognizing ribosomal protein L7.The regulation of murine lupus.Nucleosome-driven autoimmune response in lupus. Pathogenic T helper cell epitopes and costimulatory signals.T and B cell recognition of idiotypes of anti-DNA autoantibodies.Tracking early autoimmune disease by bioluminescent imaging of NF-kappaB activation reveals pathology in multiple organ systems.Self Ig peptides that help anti-DNA antibody production: importance of charged residues.

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P2860

T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus

http://www.wikidata.org/entity/Q36364979

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1995 nî lūn-bûn

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1995年学术文章

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1995年学术文章

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1995年学术文章

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1995年學術文章

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T cell determinants from autoa ...... e systemic lupus erythematosus

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T cell determinants from autoa ...... e systemic lupus erythematosus

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type

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T cell determinants from autoa ...... e systemic lupus erythematosus

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T cell determinants from autoa ...... e systemic lupus erythematosus

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prefLabel

T cell determinants from autoa ...... e systemic lupus erythematosus

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T cell determinants from autoa ...... e systemic lupus erythematosus

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T cell determinants from autoa ...... e systemic lupus erythematosus

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A Sette

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B H Hahn

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E E Sercarz

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F M Ebling

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R R Singh

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S Southwood

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V Kumar

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P2860

Sequence analysis of peptides bound to MHC class II molecules

Mixed haplotypes and autoimmunity.

Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells.

Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition.

Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4.

An immunoglobulin light chain from a lupus-prone mouse induces autoantibodies in normal mice

Induction of a cationic shift in IgG anti-DNA autoantibodies. Role of T helper cells with classical and novel phenotypes in three murine models of lupus nephritis

Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus

Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles.

Lymphokine control of in vivo immunoglobulin isotype selection.

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2017-2027

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scholarly article

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10.1084/JEM.181.6.2017

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6

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181

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1995-06-01T00:00:00Z

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277515185

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7539036

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2192064

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