Induction of the early growth response (Egr) family of transcription factors during thymic selection.
about
Themis, a T cell-specific protein important for late thymocyte developmentTOX provides a link between calcineurin activation and CD8 lineage commitmentβ-catenin/TCF-1 pathway in T cell development and differentiationRegulation of GATA-3 expression during CD4 lineage differentiation.The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3Lck SH3 domain function is required for T-cell receptor signals regulating thymocyte development.Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade.Overlapping and asymmetric functions of TCR signaling during thymic selection of CD4 and CD8 lineagesCyclosporin A-sensitive transcription factor Egr-3 regulates Fas ligand expression.Early growth response gene-2 (Egr-2) regulates the development of B and T cells.The Ras/MAPK pathway is required for generation of iNKT cells.A requirement for sustained ERK signaling during thymocyte positive selection in vivo.Tenuous paths in unexplored territory: From T cell receptor signaling to effector gene expression during thymocyte selection.Chromatin remodeling complex NURF regulates thymocyte maturation.Costimulatory signals are required for induction of transcription factor Nur77 during negative selection of CD4(+)CD8(+) thymocytes.Zfat-deficiency results in a loss of CD3ζ phosphorylation with dysregulation of ERK and Egr activities leading to impaired positive selection.Pak2 Controls Acquisition of NKT Cell Fate by Regulating Expression of the Transcription Factors PLZF and Egr2.Recent insights into the signals that control alphabeta/gammadelta-lineage fate.Commitment issues: linking positive selection signals and lineage diversification in the thymus.The transcription factor early growth response 1 (Egr-1) advances differentiation of pre-B and immature B cells.Modulation of thymic selection by expression of an immediate-early gene, early growth response 1 (Egr-1).Opposing regulation of T cell function by Egr-1/NAB2 and Egr-2/Egr-3.Egr2 is required for Bcl-2 induction during positive selection.The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cellsComparison of DNA vaccines producing HIV-1 Gag and LAMP/Gag chimera in rhesus macaques reveals antigen-specific T-cell responses with distinct phenotypes.Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals.Egr3 induces a Th17 response by promoting the development of γδ T cells.Towards a molecular understanding of the differential signals regulating alphabeta/gammadelta T lineage choice.Two distinct steps during thymocyte maturation from CD4-CD8- to CD4+CD8+ distinguished in the early growth response (Egr)-1 transgenic mice with a recombinase-activating gene-deficient background.Early growth response protein-1 (Egr-1) is preferentially expressed in T helper type 2 (Th2) cells and is involved in acute transcription of the Th2 cytokine interleukin-4.Tcra enhancer activation by inducible transcription factors downstream of pre-TCR signaling.GPER mediates the Egr-1 expression induced by 17β-estradiol and 4-hydroxitamoxifen in breast and endometrial cancer cells.The role of MAPKs in B cell receptor-induced down-regulation of Egr-1 in immature B lymphoma cells.A Zap70-dependent feedback circuit is essential for efficient selection of CD4 lineage thymocytes.Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling.The early growth response factor-1 contributes to interleukin-13 production by mast cells in response to stem cell factor stimulation.Phosphatidylinositol 3-kinase improves the efficiency of positive selection.Nab2 maintains thymus cellularity with aging and stress.Serum Response Factor Contributes Selectively to Lymphocyte Development
P2860
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P2860
Induction of the early growth response (Egr) family of transcription factors during thymic selection.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Induction of the early growth ...... ctors during thymic selection.
@ast
Induction of the early growth ...... ctors during thymic selection.
@en
type
label
Induction of the early growth ...... ctors during thymic selection.
@ast
Induction of the early growth ...... ctors during thymic selection.
@en
prefLabel
Induction of the early growth ...... ctors during thymic selection.
@ast
Induction of the early growth ...... ctors during thymic selection.
@en
P2093
P2860
P356
P1476
Induction of the early growth ...... ctors during thymic selection.
@en
P2093
P2860
P304
P356
10.1084/JEM.185.4.731
P407
P577
1997-02-01T00:00:00Z