Potential immunocompetence of proteolytic fragments produced by proteasomes before evolution of the vertebrate immune system.
about
Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidaseComputational prediction of cleavage using proteasomal in vitro digestion and MHC I ligand data.Identification of novel HLA-B27 ligands derived from polymorphic regions of its own or other class I molecules based on direct generation by 20 S proteasome.Identification and linkage of the proteasome activator complex PA28 subunit genes in zebrafish.Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1.Tapasin enhances assembly of transporters associated with antigen processing-dependent and -independent peptides with HLA-A2 and HLA-B27 expressed in insect cells.A comparison of viral immune escape strategies targeting the MHC class I assembly pathway.The proteasome activator 11 S REG (PA28) and class I antigen presentationThe specificity of proteasomes: impact on MHC class I processing and presentation of antigens.Proteolysis and class I major histocompatibility complex antigen presentation.Contribution of proteasomal beta-subunits to the cleavage of peptide substrates analyzed with yeast mutants.Mechanisms of MHC class I-restricted antigen presentation.The major histocompatibility complex origin.Cytotoxic T lymphocyte epitopes of HIV-1 Nef: Generation of multiple definitive major histocompatibility complex class I ligands by proteasomes.Efficient generation of a hepatitis B virus cytotoxic T lymphocyte epitope requires the structural features of immunoproteasomes.The sequence alteration associated with a mutational hotspot in p53 protects cells from lysis by cytotoxic T lymphocytes specific for a flanking peptide epitope.Follicle cell proteasome activity and acid extract from the egg vitelline coat prompt the onset of self-sterility in Ciona intestinalis oocytes.Proteasome allostery as a population shift between interchanging conformersPromises and limitations of murine models in the development of anticancer T-cell vaccines.Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation.Structure and Dynamics of Antigenic Peptides in Complex with TAP.PA28 and the proteasome immunosubunits play a central and independent role in the production of MHC class I-binding peptides in vivo.Differential influence on cytotoxic T lymphocyte epitope presentation by controlled expression of either proteasome immunosubunits or PA28Retention of empty MHC class I molecules by tapasin is essential to reconstitute antigen presentation in invertebrate cellsPrediction of proteasome cleavage motifs by neural networks.Co-evolution of a primordial peptide-presentation system and cellular immunity.Churchill and the immune system of ectothermic vertebrates
P2860
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P2860
Potential immunocompetence of proteolytic fragments produced by proteasomes before evolution of the vertebrate immune system.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Potential immunocompetence of ...... the vertebrate immune system.
@ast
Potential immunocompetence of ...... the vertebrate immune system.
@en
type
label
Potential immunocompetence of ...... the vertebrate immune system.
@ast
Potential immunocompetence of ...... the vertebrate immune system.
@en
prefLabel
Potential immunocompetence of ...... the vertebrate immune system.
@ast
Potential immunocompetence of ...... the vertebrate immune system.
@en
P2093
P2860
P356
P1476
Potential immunocompetence of ...... the vertebrate immune system.
@en
P2093
C Gartmann
G Niedermann
K Eichmann
M C Rechsteiner
P2860
P304
P356
10.1084/JEM.186.2.209
P407
P577
1997-07-01T00:00:00Z