A critical role for the programmed death ligand 1 in fetomaternal tolerance. - Test2 - elhamkhani - TriplyDB

A critical role for the programmed death ligand 1 in fetomaternal tolerance.

A critical role for the programmed death ligand 1 in fetomaternal tolerance.

http://www.wikidata.org/entity/Q36403162

about

Role of the PD-1 pathway in the immune response NK cells in immunotolerant organs The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors The PD1:PD-L1/2 Pathway from Discovery to Clinical Implementation The role of the PD-1 pathway in autoimmunity and peripheral tolerance VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses Inhibitory TCR coreceptor PD-1 is a sensitive indicator of low-level replication of SIV and HIV-1 Innate immune system and preeclampsia.Expression of inhibitory receptors and polyfunctional responses of T cells are linked to the risk of congenital transmission of T. cruzi.Maternal CD4⁺ and CD8⁺ T cell tolerance towards a fetal minor histocompatibility antigen in T cell receptor transgenic mice CXCL10 and IL-6: Markers of two different forms of intra-amniotic inflammation in preterm labor.PD-1 regulates T cell proliferation in a tissue and subset-specific manner during normal mouse pregnancy Immune surveillance of the maternal/fetal interface: controversies and implications.PD-L1 is increased in the spinal cord and infiltrating lymphocytes in experimental allergic encephalomyelitis An immunological insight into the origins of pre-eclampsia.Preventive and therapeutic potential of placental extract in contact hypersensitivity Physiological and molecular determinants of embryo implantation VISTA is an immune checkpoint molecule for human T cells.Perinatal Listeria monocytogenes susceptibility despite preconceptual priming and maintenance of pathogen-specific CD8(+) T cells during pregnancy.Recent Insight into the Role of the PD-1/PD-L1 Pathway in Feto-Maternal Tolerance and Pregnancy.CD106 identifies a subpopulation of mesenchymal stem cells with unique immunomodulatory properties.Lack of PD-L1 expression by iNKT cells improves the course of influenza A infection.PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection.Fetal intervention increases maternal T cell awareness of the foreign conceptus and can lead to immune-mediated fetal demise.Costimulation couture: a designer approach to regulating autoimmunity.Characterization of regulatory dendritic cells that mitigate acute graft-versus-host disease in older mice following allogeneic bone marrow transplantation.B7-H1 expression is associated with poor prognosis in colorectal carcinoma and regulates the proliferation and invasion of HCT116 colorectal cancer cells.Tissue-specific expression of B7x protects from CD4 T cell-mediated autoimmunity.The link between the PDL1 costimulatory pathway and Th17 in fetomaternal tolerance.Immune-checkpoint proteins VISTA and PD-1 nonredundantly regulate murine T-cell responses.Neisseria gonorrhoeae Modulates Immunity by Polarizing Human Macrophages to a M2 Profile Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus.Association between PD-1/PD-L1 and T regulate cells in early recurrent miscarriage.Biomarkers of transplantation tolerance: more hopeful than helpful?Neisseria gonorrhoeae suppresses dendritic cell-induced, antigen-dependent CD4 T cell proliferation B7 family molecules as regulators of the maternal immune system in pregnancy Tissue expression of PD-L1 mediates peripheral T cell tolerance.New battlefields for costimulation.Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction.What is the role of regulatory T cells in the success of implantation and early pregnancy?

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P2860

A critical role for the programmed death ligand 1 in fetomaternal tolerance.

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A critical role for the programmed death ligand 1 in fetomaternal tolerance.

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A critical role for the programmed death ligand 1 in fetomaternal tolerance.

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Andrew L Mellor

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Anthony Coyle

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Antje Habicht

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Arezou Khosroshahi

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Hideo Yagita

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Indira Guleria

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Miyuki Azuma

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Mohamed H Sayegh

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Mohammed Javeed Ansari

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Randolph J Noelle

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P2860

B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion

Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death

Prevention of allogeneic fetal rejection by tryptophan catabolism

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

TRAIL (Apo-2L) and TRAIL receptors in human placentas: implications for immune privilege

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2

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