Crystallization and preliminary X-ray analysis of a U2AF65 variant in complex with a polypyrimidine-tract analogue by use of protein engineering
about
An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signalStructure of the central RNA recognition motif of human TIA-1 at 1.95Å resolutionU2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA.Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65.A serendipitous discovery that in situ proteolysis is essential for the crystallization of yeast CPSF-100 (Ydh1p).Solution conformation and thermodynamic characteristics of RNA binding by the splicing factor U2AF65Roles of polypyrimidine tract binding proteins in major immediate-early gene expression and viral replication of human cytomegalovirus.
P2860
Q27324522-E17DAADF-93F3-492B-82FE-9EDA40DE6A09Q27649550-C8C88B3F-1434-477E-B814-A4F57D0569D8Q27676123-7B395580-0DCA-42DE-A3AB-093DA89004DCQ34709228-4D23EFE2-562A-4F2D-8BBC-B0242A089D39Q36094616-93DAE7A8-EB1C-4E1D-B66A-D810B8116678Q36426286-984DD094-6649-454D-897B-62B93A84C0F2Q36980973-97AC4527-12F0-4481-BD65-824F1267DFF1Q39895219-D622AA03-8141-4B7A-90D0-32479655CF23
P2860
Crystallization and preliminary X-ray analysis of a U2AF65 variant in complex with a polypyrimidine-tract analogue by use of protein engineering
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Crystallization and preliminar ...... by use of protein engineering
@ast
Crystallization and preliminar ...... by use of protein engineering
@en
type
label
Crystallization and preliminar ...... by use of protein engineering
@ast
Crystallization and preliminar ...... by use of protein engineering
@en
prefLabel
Crystallization and preliminar ...... by use of protein engineering
@ast
Crystallization and preliminar ...... by use of protein engineering
@en
P2860
P1476
Crystallization and preliminar ...... by use of protein engineering
@en
P2093
E Allen Sickmier
Katherine E Frato
P2860
P304
P356
10.1107/S1744309106012504
P577
2006-04-12T00:00:00Z