Cell-intrinsic IL-27 and gp130 cytokine receptor signaling regulates virus-specific CD4⁺ T cell responses and viral control during chronic infection.
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Molecular and cellular insights into T cell exhaustionInnate and Adaptive Immune Regulation During Chronic Viral InfectionsThe regulation of T follicular helper responses during infectionGene expression profiling of the response to interferon beta in Epstein-Barr-transformed and primary B cells of patients with multiple sclerosisSelection on Network Dynamics Drives Differential Rates of Protein Domain EvolutionAn image-based genetic assay identifies genes in T1D susceptibility loci controlling cellular antiviral immunity in mouseIL-27 limits central nervous system viral clearance by promoting IL-10 and enhances demyelination.Glycogen Synthase Kinase 3 Inactivation Drives T-bet-Mediated Downregulation of Co-receptor PD-1 to Enhance CD8(+) Cytolytic T Cell Responses.IL-27 is required for shaping the magnitude, affinity distribution, and memory of T cells responding to subunit immunization.The transforming growth factor beta signaling pathway is critical for the formation of CD4 T follicular helper cells and isotype-switched antibody responses in the lung mucosa.New insights into type I interferon and the immunopathogenesis of persistent viral infections.Cell-Intrinsic gp130 Signaling on CD4+ T Cells Shapes Long-Lasting Antiviral ImmunityIFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection.Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence.IL-27 Limits Type 2 Immunopathology Following Parainfluenza Virus Infection.A Critical Role of IL-21-Induced BATF in Sustaining CD8-T-Cell-Mediated Chronic Viral Control.T follicular helper cell differentiation, function, and roles in disease.T follicular helper (Tfh ) cells in normal immune responses and in allergic disorders.T follicular helper cell programming by cytokine-mediated events.IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice.Interleukin-27 signalling induces stem cell antigen-1 expression in T lymphocytes in vivo.IL-6 promotes CD4+ T-cell and B-cell activation during Plasmodium infection.Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology.CD4+ T Cell Differentiation in Chronic Viral Infections: The Tfh Perspective.Interleukin-27R Signaling Mediates Early Viral Containment and Impacts Innate and Adaptive Immunity after Chronic Lymphocytic Choriomeningitis Virus Infection.The Janus Face of Follicular T Helper Cells in Chronic Viral Infections.Harnessing T Follicular Helper Cell Responses for HIV Vaccine Development
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P2860
Cell-intrinsic IL-27 and gp130 cytokine receptor signaling regulates virus-specific CD4⁺ T cell responses and viral control during chronic infection.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
Cell-intrinsic IL-27 and gp130 ...... trol during chronic infection.
@ast
Cell-intrinsic IL-27 and gp130 ...... trol during chronic infection.
@en
type
label
Cell-intrinsic IL-27 and gp130 ...... trol during chronic infection.
@ast
Cell-intrinsic IL-27 and gp130 ...... trol during chronic infection.
@en
prefLabel
Cell-intrinsic IL-27 and gp130 ...... trol during chronic infection.
@ast
Cell-intrinsic IL-27 and gp130 ...... trol during chronic infection.
@en
P2860
P1433
P1476
Cell-intrinsic IL-27 and gp130 ...... trol during chronic infection.
@en
P2093
Aleksandr Dolgoter
Elina I Zuniga
P2860
P304
P356
10.1016/J.IMMUNI.2013.08.010
P407
P50
P577
2013-08-29T00:00:00Z