Gating and conductance properties of BK channels are modulated by the S9-S10 tail domain of the alpha subunit. A study of mSlo1 and mSlo3 wild-type and chimeric channels.
about
Gating mechanism of BK (Slo1) channels: so near, yet so farSlo3 K+ channels: voltage and pH dependence of macroscopic currentsCysteine residue 911 in C-terminal tail of human BK(Ca)α channel subunit is crucial for its activation by carbon monoxide.Stepwise contribution of each subunit to the cooperative activation of BK channels by Ca2+.A ring of eight conserved negatively charged amino acids doubles the conductance of BK channels and prevents inward rectification.Ring of negative charge in BK channels facilitates block by intracellular Mg2+ and polyamines through electrostatics.Intra- and intersubunit cooperativity in activation of BK channels by Ca2+Modes of operation of the BKCa channel beta2 subunit.Slo1 tail domains, but not the Ca2+ bowl, are required for the beta 1 subunit to increase the apparent Ca2+ sensitivity of BK channelsElimination of the BK(Ca) channel's high-affinity Ca(2+) sensitivity.Molecular Determinants of BK Channel Functional Diversity and Functioning.The cytoplasmic tail of large conductance, voltage- and Ca2+-activated K+ (MaxiK) channel is necessary for its cell surface expression.Hydrophobic interface between two regulators of K+ conductance domains critical for calcium-dependent activation of large conductance Ca2+-activated K+ channels.
P2860
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P2860
Gating and conductance properties of BK channels are modulated by the S9-S10 tail domain of the alpha subunit. A study of mSlo1 and mSlo3 wild-type and chimeric channels.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
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2001年學術文章
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2001年學術文章
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name
Gating and conductance propert ...... ld-type and chimeric channels.
@ast
Gating and conductance propert ...... ld-type and chimeric channels.
@en
type
label
Gating and conductance propert ...... ld-type and chimeric channels.
@ast
Gating and conductance propert ...... ld-type and chimeric channels.
@en
prefLabel
Gating and conductance propert ...... ld-type and chimeric channels.
@ast
Gating and conductance propert ...... ld-type and chimeric channels.
@en
P2860
P356
P1476
Gating and conductance propert ...... ld-type and chimeric channels.
@en
P2093
P2860
P304
P356
10.1085/JGP.118.6.711
P577
2001-12-01T00:00:00Z