Hallucinogen actions on 5-HT receptors reveal distinct mechanisms of activation and signaling by G protein-coupled receptors.
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3D structure prediction of human β1-adrenergic receptor via threading-based homology modeling for implications in structure-based drug designingAnimal models of serotonergic psychedelics.Pharmacological properties and discriminative stimulus effects of a novel and selective 5-HT2 receptor agonist AL-38022A [(S)-2-(8,9-dihydro-7H-pyrano[2,3-g]indazol-1-yl)-1-methylethylamine].Manganese-enhanced magnetic resonance imaging reveals increased DOI-induced brain activity in a mouse model of schizophrenia.Modeling activated states of GPCRs: the rhodopsin template.Structural and dynamic effects of cholesterol at preferred sites of interaction with rhodopsin identified from microsecond length molecular dynamics simulations.Cholesterol modulates the membrane effects and spatial organization of membrane-penetrating ligands for G-protein coupled receptorsLigand-dependent conformations and dynamics of the serotonin 5-HT(2A) receptor determine its activation and membrane-driven oligomerization propertiesA minimal ligand binding pocket within a network of correlated mutations identified by multiple sequence and structural analysis of G protein coupled receptors.Probing the structural determinants for the function of intracellular loop 2 in structurally cognate G-protein-coupled receptors.Towards a quantitative representation of the cell signaling mechanisms of hallucinogens: measurement and mathematical modeling of 5-HT1A and 5-HT2A receptor-mediated ERK1/2 activationMolecular dynamics simulation study of a pulmonary surfactant film interacting with a carbonaceous nanoparticle.Molecular pharmacology and ligand docking studies reveal a single amino acid difference between mouse and human serotonin 5-HT2A receptors that impacts behavioral translation of novel 4-phenyl-2-dimethylaminotetralin ligandsIn silico Exploration of the Conformational Universe of GPCRs.Light activation of rhodopsin: insights from molecular dynamics simulations guided by solid-state NMR distance restraints.Neurobiologische Grundlagen der Wirkung von Psychedelika
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P2860
Hallucinogen actions on 5-HT receptors reveal distinct mechanisms of activation and signaling by G protein-coupled receptors.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Hallucinogen actions on 5-HT r ...... y G protein-coupled receptors.
@ast
Hallucinogen actions on 5-HT r ...... y G protein-coupled receptors.
@en
type
label
Hallucinogen actions on 5-HT r ...... y G protein-coupled receptors.
@ast
Hallucinogen actions on 5-HT r ...... y G protein-coupled receptors.
@en
prefLabel
Hallucinogen actions on 5-HT r ...... y G protein-coupled receptors.
@ast
Hallucinogen actions on 5-HT r ...... y G protein-coupled receptors.
@en
P2860
P356
P1433
P1476
Hallucinogen actions on 5-HT r ...... y G protein-coupled receptors.
@en
P2093
Harel Weinstein
P2860
P2888
P304
P356
10.1208/AAPSJ070485
P407
P577
2005-01-01T00:00:00Z
P5875
P6179
1003671566