Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway.
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Fc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeuticsCross-presentation of IgG-containing immune complexesFc-fusion technology and recombinant FVIII and FIX in the management of the hemophiliasUnraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based TherapeuticsImmunoglobulin Fc Heterodimer Platform Technology: From Design to Applications in Therapeutic Antibodies and ProteinsTargeting FcRn for the modulation of antibody dynamicsNeonatal Fc receptor and IgG-based therapeuticsThe neonatal Fc receptor, FcRn, as a target for drug delivery and therapyCharacterization of protein factor(s) in rat bronchoalveolar lavage fluid that enhance insulin transport via transcytosis across primary rat alveolar epithelial cell monolayersThe role of disposable inhalers in pulmonary drug delivery.The recycling and transcytotic pathways for IgG transport by FcRn are distinct and display an inherent polarity.Post-exposure vaccination improves gammaherpesvirus neutralizationTargeting FcRn for therapy: from live cell imaging to in vivo studies in mice.Engineered clearing agents for the selective depletion of antigen-specific antibodiesA von Willebrand factor fragment containing the D'D3 domains is sufficient to stabilize coagulation factor VIII in miceRecombinant FIXFc: a novel therapy for the royal disease?Simulation of monoclonal antibody pharmacokinetics in humans using a minimal physiologically based model.New strategies for enzyme replacement therapy for lysosomal storage diseasesSelection of nanobodies that target human neonatal Fc receptor.Generation of biologically active multi-sialylated recombinant human EPOFc in plants.Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteriaRegulation of immune responses by the neonatal fc receptor and its therapeutic implicationsCytoprotective effect of recombinant human erythropoietin produced in transgenic tobacco plants.Robust expression of the human neonatal Fc receptor in a truncated soluble form and as a full-length membrane-bound protein in fusion with eGFPA neonatal Fc receptor-targeted mucosal vaccine strategy effectively induces HIV-1 antigen-specific immunity to genital infection.Enhanced neonatal Fc receptor function improves protection against primate SHIV infection.FcRn: The Architect Behind the Immune and Nonimmune Functions of IgG and Albumin.Soluble monomeric IgG1 Fc.Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-lifeMucosal antibodies in the regulation of tolerance and allergy to foods.Characterization of 99mTc-labeled cytokine ligands for inflammation imaging via TNF and IL-1 pathwaysCommercial challenges of protein drug delivery.Ca2+-dependent calmodulin binding to FcRn affects immunoglobulin G transport in the transcytotic pathwayThe immunologic functions of the neonatal Fc receptor for IgGTargeting receptor-mediated endocytotic pathways with nanoparticles: rationale and advances.Infused Fc-tagged beta-glucuronidase crosses the placenta and produces clearance of storage in utero in mucopolysaccharidosis VII mice.Design of fine particles for pulmonary drug delivery.FcRn binding is not sufficient for achieving systemic therapeutic levels of immunoglobulin G after oral delivery of enteric-coated capsules in cynomolgus macaquesAntibodies and their receptors: different potential roles in mucosal defense.Pharmacokinetics of recombinant bifunctional fusion proteins.
P2860
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P2860
Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Pulmonary delivery of an eryth ...... unoglobulin transport pathway.
@ast
Pulmonary delivery of an eryth ...... unoglobulin transport pathway.
@en
type
label
Pulmonary delivery of an eryth ...... unoglobulin transport pathway.
@ast
Pulmonary delivery of an eryth ...... unoglobulin transport pathway.
@en
prefLabel
Pulmonary delivery of an eryth ...... unoglobulin transport pathway.
@ast
Pulmonary delivery of an eryth ...... unoglobulin transport pathway.
@en
P2093
P2860
P356
P1476
Pulmonary delivery of an eryth ...... unoglobulin transport pathway.
@en
P2093
Alan J Bitonti
Ana Maria Garcia
Cristina A Tan
Gerburg M Spiekermann
James M Stattel
Jeffrey J Song
Jennifer A Dumont
Keith E Kropp
Neil E Simister
Richard S Blumberg
P2860
P304
P356
10.1073/PNAS.0403235101
P407
P577
2004-06-21T00:00:00Z