Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis.
about
Rational and combinatorial tailoring of bioactive cyclic dipeptidesThe tRNA-dependent biosynthesis of modified cyclic dipeptidesExpanding P450 catalytic reaction space through evolution and engineeringStructural Insights into the Mechanism for Recognizing Substrate of the Cytochrome P450 Enzyme TxtEConversion of fatty aldehydes into alk (a/e)nes by in vitro reconstituted cyanobacterial aldehyde-deformylating oxygenase with the cognate electron transfer systemTyrosine-Nitrated Proteins: Proteomic and Bioanalytical Aspects.Direct nitration and azidation of aliphatic carbons by an iron-dependent halogenaseEnzyme-controlled nitrogen-atom transfer enables regiodivergent C-H amination.Structural, functional, and spectroscopic characterization of the substrate scope of the novel nitrating cytochrome P450 TxtE.Non-natural olefin cyclopropanation catalyzed by diverse cytochrome P450s and other hemoproteins.The cellobiose sensor CebR is the gatekeeper of Streptomyces scabies pathogenicitySubstrate Hunting for the Myxobacterial CYP260A1 Revealed New 1α-Hydroxylated Products from C-19 Steroids.Enantioselective Enzyme-Catalyzed Aziridination Enabled by Active-Site Evolution of a Cytochrome P450Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation.Engineered P450 biocatalysts show improved activity and regio-promiscuity in aromatic nitration.Discovery of a regioselectivity switch in nitrating P450s guided by molecular dynamics simulations and Markov models.Unusual cytochrome p450 enzymes and reactions.New reactions and products resulting from alternative interactions between the P450 enzyme and redox partners.Tentative biosynthetic pathways of some microbial diketopiperazines.Phytotoxins produced by plant pathogenic Streptomyces species.Cytochromes P450 as promising catalysts for biotechnological application: chances and limitations.Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function.Design and engineering of artificial oxygen-activating metalloenzymes.Diversity of nature's assembly lines - recent discoveries in non-ribosomal peptide synthesis.Biosynthesis of ilamycins featuring unusual building blocks and engineered production of enhanced anti-tuberculosis agents.Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis.Genome Content and Phylogenomics Reveal both Ancestral and Lateral Evolutionary Pathways in Plant-Pathogenic Streptomyces Species.Unlocking Reactivity of TrpB: A General Biocatalytic Platform for Synthesis of Tryptophan AnaloguesCyanobacterial Sfp-type phosphopantetheinyl transferases functionalize carrier proteins of diverse biosynthetic pathways.Generate a bioactive natural product library by mining bacterial cytochrome P450 patterns.A Six-Coordinate Peroxynitrite Low-Spin Iron(III) Porphyrinate Complex-The Product of the Reaction of Nitrogen Monoxide (·NO(g)) with a Ferric-Superoxide Species.Production of Stealthin C Involves an S-N-Type Smiles Rearrangement.A Peroxynitrite Dicopper Complex: Formation via Cu-NO and Cu-O2 Intermediates and Reactivity via O-O Cleavage Chemistry.Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins.Cyclodipeptides: An Overview of Their Biosynthesis and Biological Activity.Identification and characterization of a bacterial cytochrome P450 monooxygenase catalyzing the 3-nitration of tyrosine in rufomycin biosynthesis.Expansion of chemical space for natural products by uncommon P450 reactions.Efficient methylation of C2 in l-tryptophan by the cobalamin-dependent radical S-adenosylmethionine methylase TsrM requires an unmodified N1 amine.Copper(I)/NO(g) Reductive Coupling Producing a trans-Hyponitrite Bridged Dicopper(II) Complex: Redox Reversal Giving Copper(I)/NO(g) Disproportionation.An artificial self-sufficient cytochrome P450 directly nitrates fluorinated tryptophan analogs with a different regio-selectivity.
P2860
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P2860
Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis.
@ast
Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis.
@en
type
label
Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis.
@ast
Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis.
@en
prefLabel
Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis.
@ast
Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis.
@en
P2093
P2860
P50
P356
P1476
Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis.
@en
P2093
Bhumit Patel
Brian R Crane
Donna M Gibson
Johan A Kers
Lijiang Song
Philip R Aston
Rosemary Loria
Stuart B Krasnoff
P2860
P2888
P304
P356
10.1038/NCHEMBIO.1048
P577
2012-10-01T00:00:00Z