Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity

about

Microtubule Motors Drive Hedgehog Signaling in Primary Cilia.Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action.Parasite motility is critical for virulence of African trypanosomes.

P2860

Q38986584-0D227115-CB16-4D48-8C90-56A796360332 Q41084316-4443B397-ED9A-4423-823F-3F08FAA3A1E0 Q55285586-D10CB7FB-660A-485A-B128-EEA233A82535

P2860

Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity

Item

http://www.wikidata.org/entity/Q36470713

description

2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年学术文章

@wuu

2015年学术文章

@zh-cn

2015年学术文章

@zh-hans

2015年学术文章

@zh-my

2015年学术文章

@zh-sg

2015年學術文章

@yue

2015年學術文章

@zh

2015年學術文章

@zh-hant

name

Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity

@ast

Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity

@en

type

Item

label

Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity

@ast

Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity

@en

prefLabel

Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity

@ast

Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity

@en

P1476

Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity

@en

P2093

Andrew H Chung

http://www.w3.org/2001/XMLSchema#string

Fan Ye

http://www.w3.org/2001/XMLSchema#string

Jonathan B Steinman

http://www.w3.org/2001/XMLSchema#string

Rand M Miller

http://www.w3.org/2001/XMLSchema#string

Ruta Zalyte

http://www.w3.org/2001/XMLSchema#string

Stephanie K See

http://www.w3.org/2001/XMLSchema#string

Tarun M Kapoor

http://www.w3.org/2001/XMLSchema#string

Tommaso Cupido

http://www.w3.org/2001/XMLSchema#string

Tomoyo Sakata-Kato

http://www.w3.org/2001/XMLSchema#string

P2860

Cytoplasmic dynein plays a role in mammalian mitotic spindle formation

Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles

Identification of a novel light intermediate chain (D2LIC) for mammalian cytoplasmic dynein 2.

Crystal structure of the kinesin motor domain reveals a structural similarity to myosin

Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation

The 2.8 Å crystal structure of the dynein motor domain

Insights into dynein motor domain function from a 3.3-Å crystal structure

Cytoplasmic dynein heavy chain 1b is required for flagellar assembly in Chlamydomonas.

Functions and mechanics of dynein motor proteins

Cilia and Hedgehog responsiveness in the mouse

P304

53-60

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1021/ACSCHEMBIO.5B00895

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

P577

2015-11-11T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

26555042

http://www.w3.org/2001/XMLSchema#string

P932

4715766

http://www.w3.org/2001/XMLSchema#string

Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity

about

P2860

P2860

Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932