Human cytomegalovirus microRNA miR-US4-1 inhibits CD8(+) T cell responses by targeting the aminopeptidase ERAP1 - Test2 - elhamkhani - TriplyDB

Human cytomegalovirus microRNA miR-US4-1 inhibits CD8(+) T cell responses by targeting the aminopeptidase ERAP1

Human cytomegalovirus microRNA miR-US4-1 inhibits CD8(+) T cell responses by targeting the aminopeptidase ERAP1

http://www.wikidata.org/entity/Q36479743

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The Role of microRNAs in the Pathogenesis of Herpesvirus Infection Pathogens Use and Abuse MicroRNAs to Deceive the Immune System MicroRNAs Expressed during Viral Infection: Biomarker Potential and Therapeutic Considerations Human cytomegalovirus and autoimmune disease Immune surveillance for ERAAP dysfunction Immune regulation of human herpesviruses and its implications for human transplantation Endoplasmic reticulum aminopeptidase-1 functions regulate key aspects of the innate immune response microRNAs function in CD8+T cell biology Nonclassical MHC class Ib-restricted cytotoxic T cells monitor antigen processing in the endoplasmic reticulum Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation Manipulation of Viral MicroRNAs as a Potential Antiviral Strategy for the Treatment of Cytomegalovirus Infection.Distinct expression profile of HCMV encoded miRNAs in plasma from oral lichen planus patients.Expression of the human cytomegalovirus UL11 glycoprotein in viral infection and evaluation of its effect on virus-specific CD8 T cells.Functionally distinct ERAP1 allotype combinations distinguish individuals with Ankylosing Spondylitis.Incorporating alternative splicing and mRNA editing into the genetic analysis of complex traits.Viral noncoding RNAs: more surprises.High-resolution profiling and analysis of viral and host small RNAs during human cytomegalovirus infection.Immunotherapy with Donor T Cells Sensitized with Overlapping Pentadecapeptides for Treatment of Persistent Cytomegalovirus Infection or Viremia.Role of endoplasmic reticulum aminopeptidases in health and disease: from infection to cancer.Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (ER) Aminopeptidase 2 The immunology of human cytomegalovirus latency: could latent infection be cleared by novel immunotherapeutic strategies?Increasing expression of microRNA 181 inhibits porcine reproductive and respiratory syndrome virus replication and has implications for controlling virus infection.Circulating human cytomegalovirus-encoded HCMV-miR-US4-1 as an indicator for predicting the efficacy of IFNα treatment in chronic hepatitis B patients.The expression of interleukin-32 is activated by human cytomegalovirus infection and down regulated by hcmv-miR-UL112-1 Constitutive Lck Activity Drives Sensitivity Differences between CD8+ Memory T Cell Subsets.ERAAP and tapasin independently edit the amino and carboxyl termini of MHC class I peptides.Ankylosing spondylitis: from cells to genes p53 increases MHC class I expression by upregulating the endoplasmic reticulum aminopeptidase ERAP1 Don't mess with ERAAP!Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.Monitoring peptide processing for MHC class I molecules in the endoplasmic reticulum.The genetic basis for individual differences in mRNA splicing and APOBEC1 editing activity in murine macrophages.MicroRNAs in the regulation of TLR and RIG-I pathways.Diverse immune evasion strategies by human cytomegalovirus.Autoimmunity in 2011.Dendritic cell biology in human cytomegalovirus infection and the clinical consequences for host immunity and pathology.MicroRNAs as mediators of viral evasion of the immune system.MicroRNAs and the immune response to respiratory virus infections.Endoplasmic reticulum aminopeptidase 1 function and its pathogenic role in regulating innate and adaptive immunity in cancer and major histocompatibility complex class I-associated autoimmune diseases.The intimate relationship between human cytomegalovirus and the dendritic cell lineage.

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Human cytomegalovirus microRNA miR-US4-1 inhibits CD8(+) T cell responses by targeting the aminopeptidase ERAP1

http://www.wikidata.org/entity/Q36479743

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Human cytomegalovirus microRNA ...... eting the aminopeptidase ERAP1

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Human cytomegalovirus microRNA ...... eting the aminopeptidase ERAP1

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Nature Immunology

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Human cytomegalovirus microRNA ...... eting the aminopeptidase ERAP1

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Donghyun Kim

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Irini Evnouchidou

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Jin-Hyun Ahn

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Jinwook Shin

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Kwangseog Ahn

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Sanghyun Lee

http://www.w3.org/2001/XMLSchema#string

Stanley R Riddell

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Sungchul Kim

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V Narry Kim

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Young-Eui Kim

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P2860

The nuclear RNase III Drosha initiates microRNA processing

Human leukocyte-derived arginine aminopeptidase. The third member of the oxytocinase subfamily of aminopeptidases

Fast and effective prediction of microRNA/target duplexes

Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides

Identification of virus-encoded microRNAs

Regulation of mRNA translation and stability by microRNAs

A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes

Identification of microRNAs of the herpesvirus family

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984-991

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10.1038/NI.2097

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10

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12

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Efstratios Stratikos

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2011-09-04T00:00:00Z

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51618560

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21892175

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Cytomegalovirus

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3526977

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