Design, synthesis, and biological evaluation of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4'-pyridyl)carboxamido]morphinan derivatives as peripheral selective μ opioid receptor Agents.
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Design, synthesis, and biological evaluation of 14-heteroaromatic-substituted naltrexone derivatives: pharmacological profile switch from mu opioid receptor selectivity to mu/kappa opioid receptor dual selectivityDesign, syntheses, and pharmacological characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan analogues as opioid receptor ligandsSynthesis and characterization of a dual kappa-delta opioid receptor agonist analgesic blocking cocaine reward behaviorBinding mode characterization of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives via docking in opioid receptor crystal structures and site-directed mutagenesis studies: application of the 'message-address' concept in development of mNovel 6β-acylaminomorphinans with analgesic activity.Structure activity relationship studies of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan (NAQ) analogues as potent opioid receptor ligands: preliminary results on the role of electronic characteristics forOpioid receptor selectivity profile change via isosterism for 14-O-substituted naltrexone derivatives.
P2860
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P2860
Design, synthesis, and biological evaluation of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4'-pyridyl)carboxamido]morphinan derivatives as peripheral selective μ opioid receptor Agents.
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
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name
Design, synthesis, and biologi ...... tive μ opioid receptor Agents.
@ast
Design, synthesis, and biologi ...... tive μ opioid receptor Agents.
@en
type
label
Design, synthesis, and biologi ...... tive μ opioid receptor Agents.
@ast
Design, synthesis, and biologi ...... tive μ opioid receptor Agents.
@en
prefLabel
Design, synthesis, and biologi ...... tive μ opioid receptor Agents.
@ast
Design, synthesis, and biologi ...... tive μ opioid receptor Agents.
@en
P2093
P2860
P356
P1476
Design, synthesis, and biologi ...... tive μ opioid receptor Agents.
@en
P2093
Dana E Selley
David L Stevens
Feng Zhang
Hamid I Akbarali
Irina O Beletskaya
Jianyang Chen
Krista L Scoggins
Orgil Elbegdorj
Phillip M Gerk
Shashidhar K Akubathini
P2860
P304
10118-10129
P356
10.1021/JM301247N
P407
P577
2012-11-09T00:00:00Z