Requirement of protein kinase D1 for pathological cardiac remodeling.
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Protein kinase D in vascular biology and angiogenesisProtein kinase D regulates RhoA activity via rhotekin phosphorylation.Histone deacetylase signaling in cardioprotectionProtein Kinase D1 Signaling in Angiogenic Gene Expression and VEGF-Mediated AngiogenesisPKD signaling and pancreatitisGenome-Wide Gene Expression Analysis Shows AKAP13-Mediated PKD1 Signaling Regulates the Transcriptional Response to Cardiac HypertrophyAKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to β-adrenergic-induced cardiac hypertrophyPost-translational modifications regulate class IIa histone deacetylase (HDAC) function in health and diseaseProtein kinase D increases maximal Ca2+-activated tension of cardiomyocyte contraction by phosphorylation of cMyBP-C-Ser315Distinct sarcomeric substrates are responsible for protein kinase D-mediated regulation of cardiac myofilament Ca2+ sensitivity and cross-bridge cyclingBeta-catenin phosphorylated at threonine 120 antagonizes generation of active beta-catenin by spatial localization in trans-Golgi networkA targeted library screen reveals a new inhibitor scaffold for protein kinase DUnique functions for protein kinase D1 and protein kinase D2 in mammalian cellsProtein kinase D1 (PKD1) activation mediates a compensatory protective response during early stages of oxidative stress-induced neuronal degenerationDesign, Synthesis, and Biological Evaluation of PKD Inhibitors.Regulation of PTEN activity by p38δ-PKD1 signaling in neutrophils confers inflammatory responses in the lung.Expression patterns of protein kinase D 3 during mouse developmentPotent and selective disruption of protein kinase D functionality by a benzoxoloazepinolone.Protein kinase D1 mediates class IIa histone deacetylase phosphorylation and nuclear extrusion in intestinal epithelial cells: role in mitogenic signalingPLCε, PKD1, and SSH1L transduce RhoA signaling to protect mitochondria from oxidative stress in the heart.Molecular Signals Elicited by GPCR Agonists in Hypertension, Cardiovascular Remodeling: Are MMPs and ADAMs Elusive Therapeutic Targets?Protein kinase D2 is an essential regulator of murine myoblast differentiation.The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy.Splice variants of enigma homolog, differentially expressed during heart development, promote or prevent hypertrophy.Protein kinase D as a potential new target for cancer therapy.Essential role of sympathetic endothelin A receptors for adverse cardiac remodelingHeterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy.Role of protein kinase D signaling in pancreatic cancerNovel function of cardiac protein kinase D1 as a dynamic regulator of Ca2+ sensitivity of contractionSmall heat shock protein 20 (Hsp20) facilitates nuclear import of protein kinase D 1 (PKD1) during cardiac hypertrophyProtein kinase Cθ is required for cardiomyocyte survival and cardiac remodeling.Protein kinase D controls voluntary-running-induced skeletal muscle remodellingCalcium-mediated histone modifications regulate alternative splicing in cardiomyocytes.The scaffold protein muscle A-kinase anchoring protein β orchestrates cardiac myocyte hypertrophic signaling required for the development of heart failure.Synthesis and Structure-Activity Relationships of Benzothienothiazepinone Inhibitors of Protein Kinase DProtein kinase D: coupling extracellular stimuli to the regulation of cell physiologyG protein βγ subunits regulate cardiomyocyte hypertrophy through a perinuclear Golgi phosphatidylinositol 4-phosphate hydrolysis pathway.Therapeutic efficacy of cardiosphere-derived cells in a transgenic mouse model of non-ischaemic dilated cardiomyopathy.Protein kinase D signaling: multiple biological functions in health and disease.Spatiotemporally distinct protein kinase D activation in adult cardiomyocytes in response to phenylephrine and endothelin
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P2860
Requirement of protein kinase D1 for pathological cardiac remodeling.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Requirement of protein kinase D1 for pathological cardiac remodeling.
@ast
Requirement of protein kinase D1 for pathological cardiac remodeling.
@en
type
label
Requirement of protein kinase D1 for pathological cardiac remodeling.
@ast
Requirement of protein kinase D1 for pathological cardiac remodeling.
@en
prefLabel
Requirement of protein kinase D1 for pathological cardiac remodeling.
@ast
Requirement of protein kinase D1 for pathological cardiac remodeling.
@en
P2093
P2860
P356
P1476
Requirement of protein kinase D1 for pathological cardiac remodeling.
@en
P2093
Eric N Olson
James A Richardson
Jens Fielitz
John M Shelton
Joseph A Hill
Mi-Sung Kim
Rhonda Bassel-Duby
Xiaoxia Qi
P2860
P304
P356
10.1073/PNAS.0712265105
P407
P577
2008-02-14T00:00:00Z