Oritavancin exhibits dual mode of action to inhibit cell-wall biosynthesis in Staphylococcus aureus
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Oritavancin disrupts membrane integrity of Staphylococcus aureus and vancomycin-resistant enterococci to effect rapid bacterial killingOritavancin: A New Lipoglycopeptide Antibiotic in the Treatment of Gram-Positive InfectionsThe Lantibiotic NAI-107 Binds to Bactoprenol-bound Cell Wall Precursors and Impairs Membrane FunctionsAntibiotics in the clinical pipeline at the end of 2015.Newer antibacterial drugs for a new century.Cell wall synthesis is necessary for membrane dynamics during sporulation of Bacillus subtilis.Postgenomic strategies in antibacterial drug discovery.Host-guest chemistry of the peptidoglycanStructural variations of the cell wall precursor lipid II and their influence on binding and activity of the lipoglycopeptide antibiotic oritavancin.Oritavancin diphosphateComparison of the efficacy and safety of oritavancin front-loaded dosing regimens to daily dosing: an analysis of the SIMPLIFI trial.Spectral snapshots of bacterial cell-wall composition and the influence of antibiotics by whole-cell NMR.A new understanding of antibiotic action via solid-state NMR of cells with uniform isotopic labeling.Characterization of the Vibrio cholerae extracellular matrix: a top-down solid-state NMR approach.Further insights into the mode of action of the lipoglycopeptide telavancin through global gene expression studies.Bacterial cell wall composition and the influence of antibiotics by cell-wall and whole-cell NMR.Uniformity of glycyl bridge lengths in the mature cell walls of fem mutants of methicillin-resistant Staphylococcus aureusThe isotridecanyl side chain of plusbacin-A3 is essential for the transglycosylase inhibition of peptidoglycan biosynthesisCharacterization of structural variations in the peptidoglycan of vancomycin-susceptible Enterococcus faecium: understanding glycopeptide-antibiotic binding sites using mass spectrometry.Quantitation of recombinant protein in whole cells and cell extracts via solid-state NMR spectroscopy.Hydrophobic side-chain length determines activity and conformational heterogeneity of a vancomycin derivative bound to the cell wall of Staphylococcus aureus.Oritavancin: a potential weapon in the battle against serious Gram-positive pathogens.Locations of the hydrophobic side chains of lipoglycopeptides bound to the peptidoglycan of Staphylococcus aureusSolid-state NMR characterization of amphomycin effects on peptidoglycan and wall teichoic acid biosyntheses in Staphylococcus aureus.Staphylococcus aureus peptidoglycan stem packing by rotational-echo double resonance NMR spectroscopy.Method revealing bacterial cell-wall architecture by time-dependent isotope labeling and quantitative liquid chromatography/mass spectrometryCharacterization of the peptidoglycan of vancomycin-susceptible Enterococcus faecium.Oritavancin binds to isolated protoplast membranes but not intact protoplasts of Staphylococcus aureusVancomycin and oritavancin have different modes of action in Enterococcus faeciumStaphylococcus aureus peptidoglycan tertiary structure from carbon-13 spin diffusionSurface mediated cooperative interactions of drugs enhance mechanical forces for antibiotic action.Newer developments in the treatment of Gram-positive infections.Never take candy from a stranger: the role of the bacterial glycome in host-pathogen interactions.Update on carbohydrate-containing antibacterial agents.Industrial natural product chemistry for drug discovery and development.Therapeutic options for vancomycin-resistant enterococcal bacteremia.Oritavancin for the treatment of acute bacterial skin and skin structure infections: an evidence-based review.Dalbavancin and Oritavancin: An Innovative Approach to the Treatment of Gram-Positive Infections.Lipoglycopeptide Antibacterial Agents in Gram-Positive Infections: A Comparative Review.New Found Hope for Antibiotic Discovery: Lipid II Inhibitors.
P2860
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P2860
Oritavancin exhibits dual mode of action to inhibit cell-wall biosynthesis in Staphylococcus aureus
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Oritavancin exhibits dual mode ...... hesis in Staphylococcus aureus
@ast
Oritavancin exhibits dual mode ...... hesis in Staphylococcus aureus
@en
type
label
Oritavancin exhibits dual mode ...... hesis in Staphylococcus aureus
@ast
Oritavancin exhibits dual mode ...... hesis in Staphylococcus aureus
@en
prefLabel
Oritavancin exhibits dual mode ...... hesis in Staphylococcus aureus
@ast
Oritavancin exhibits dual mode ...... hesis in Staphylococcus aureus
@en
P2093
P2860
P1476
Oritavancin exhibits dual mode ...... hesis in Staphylococcus aureus
@en
P2093
Adel Rafai Far
Dirk Stueber
Evelyne Dietrich
Jacob Schaefer
Kelly S E Tanaka
Manmilan Singh
Sung Joon Kim
Thomas R Parr
P2860
P304
P356
10.1016/J.JMB.2008.01.031
P407
P577
2008-01-17T00:00:00Z