Radiosynthesis and evaluation of [¹¹C-carbonyl]-labeled carbamates as fatty acid amide hydrolase radiotracers for positron emission tomography. - Test2 - elhamkhani - TriplyDB

Radiosynthesis and evaluation of [¹¹C-carbonyl]-labeled carbamates as fatty acid amide hydrolase radiotracers for positron emission tomography.

Radiosynthesis and evaluation of [¹¹C-carbonyl]-labeled carbamates as fatty acid amide hydrolase radiotracers for positron emission tomography.

http://www.wikidata.org/entity/Q36530102

about

(11)C[double bond, length as m-dash]O bonds made easily for positron emission tomography radiopharmaceuticals PET imaging of fatty acid amide hydrolase with [(18)F]DOPP in nonhuman primates.Total Radiosynthesis: Thinking outside "the box"Blocking of fatty acid amide hydrolase activity with PF-04457845 in human brain: a positron emission tomography study with the novel radioligand [(11)C]CURB.PET radiopharmaceuticals for probing enzymes in the brain Synthesis and Preliminary PET Imaging Studies of a FAAH Radiotracer ([¹¹C]MPPO) Based on α-Ketoheterocyclic Scaffold.11CO2 fixation: a renaissance in PET radiochemistry.Alternative approaches for PET radiotracer development in Alzheimer's disease: imaging beyond plaque.Transition metal mediated [(11) C]carbonylation reactions: recent advances and applications.New methodologies for the preparation of carbon-11 labeled radiopharmaceuticals.Discovery of MK-3168: A PET Tracer for Imaging Brain Fatty Acid Amide Hydrolase.Molecular Imaging of Hydrolytic Enzymes Using PET and SPECT.Synthesis of Diverse (11)C-Labeled PET Radiotracers via Direct Incorporation of [(11)C]CO2.Development and characterization of a promising fluorine-18 labelled radiopharmaceutical for in vivo imaging of fatty acid amide hydrolase.Synthesis and preclinical evaluation of [11C-carbonyl]PF-04457845 for neuroimaging of fatty acid amide hydrolase.Radiosynthesis and ex vivo evaluation of [(11)C-carbonyl]carbamate- and urea-based monoacylglycerol lipase inhibitors."In-loop" [11 C]CO2 fixation: Prototype and proof of concept.Carbon-11 radiolabelling of organosulfur compounds: (11) C synthesis of the progesterone receptor agonist tanaproget.Synthesis and preclinical evaluation of [¹⁸F]FCHC for neuroimaging of fatty acid amide hydrolase.A Novel Way To Radiolabel Human Butyrylcholinesterase for Positron Emission Tomography through Irreversible Transfer of the Radiolabeled Moiety.In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies.N-aryl 2-aryloxyacetamides as a new class of fatty acid amide hydrolase (FAAH) inhibitors.

P2860

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P2860

Radiosynthesis and evaluation of [¹¹C-carbonyl]-labeled carbamates as fatty acid amide hydrolase radiotracers for positron emission tomography.

http://www.wikidata.org/entity/Q36530102

description

2012 nî lūn-bûn

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Radiosynthesis and evaluation ...... positron emission tomography.

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Radiosynthesis and evaluation ...... positron emission tomography.

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Radiosynthesis and evaluation ...... positron emission tomography.

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Radiosynthesis and evaluation ...... positron emission tomography.

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Radiosynthesis and evaluation ...... r positron emission tomography

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Alan A Wilson

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Christopher J Fowler

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Jun Parkes

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Junchao Tong

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Neil Vasdev

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Oleg Sadovski

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P2860

Molecular characterization of human and mouse fatty acid amide hydrolases

Brain monoglyceride lipase participating in endocannabinoid inactivation

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol

Mechanism of carbamate inactivation of FAAH: implications for the design of covalent inhibitors and in vivo functional probes for enzymes

Monoacylglycerol lipase - a target for drug development?

Cyclohexylcarbamic acid 3'- or 4'-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure-activity relationships, and molecular modeling studies

Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

Kinetic modeling of N-[11C]methylpiperidin-4-yl propionate: alternatives for analysis of an irreversible positron emission tomography trace for measurement of acetylcholinesterase activity in human brain

Enzymatic pathways that regulate endocannabinoid signaling in the nervous system

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201-209

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10.1021/JM301492Y

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