The pathway and targeting signal for delivery of the integral membrane glycoprotein LEP100 to lysosomes.
about
AP-3: an adaptor-like protein complex with ubiquitous expression.The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membraneLIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in miceThe enhanced immune response to the HIV gp160/LAMP chimeric gene product targeted to the lysosome membrane protein trafficking pathwaymu1A-adaptin-deficient mice: lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptorsIdentification of a novel sequence involved in lysosomal sorting of the sphingolipid activator protein prosaposin.Role of the endocytic machinery in the sorting of lysosome-associated membrane proteinsIncreased LAMP-2 polylactosamine glycosylation is associated with its slower Golgi transit during establishment of a polarized MDCK epithelial monolayerTGN38 recycles basolaterally in polarized Madin-Darby canine kidney cellsE3-13.7 integral membrane proteins encoded by human adenoviruses alter epidermal growth factor receptor trafficking by interacting directly with receptors in early endosomes.The tyrosine-based lysosomal targeting signal in lamp-1 mediates sorting into Golgi-derived clathrin-coated vesicles.The cytoplasmic domain mediates localization of furin to the trans-Golgi network en route to the endosomal/lysosomal system.Cytoplasmic determinants involved in direct lysosomal sorting, endocytosis, and basolateral targeting of rat lgp120 (lamp-I) in MDCK cells.Targeting of Salmonella typhimurium to vesicles containing lysosomal membrane glycoproteins bypasses compartments with mannose 6-phosphate receptors.Efficient endosomal localization of major histocompatibility complex class II-invariant chain complexes requires multimerization of the invariant chain targeting sequence.Protein targeting by tyrosine- and di-leucine-based signals: evidence for distinct saturable componentsMutant Rab7 causes the accumulation of cathepsin D and cation-independent mannose 6-phosphate receptor in an early endocytic compartmentDifferent steady state subcellular distributions of the three splice variants of lysosome-associated membrane protein LAMP-2 are determined largely by the COOH-terminal amino acid residue.Intracellular sorting and targeting of melanosomal membrane proteins: identification of signals for sorting of the human brown locus protein, gp75A lysosomal targeting signal in the cytoplasmic tail of the beta chain directs HLA-DM to MHC class II compartments.Sorting signals in the MHC class II invariant chain cytoplasmic tail and transmembrane region determine trafficking to an endocytic processing compartment.Conformational changes of coat proteins during vesicle formation.Monomeric fluorescent timers that change color from blue to red report on cellular trafficking.How MHC class II molecules reach the endocytic pathway.Kinetic evidence that newly-synthesized endogenous lysosome-associated membrane protein-1 (LAMP-1) first transits early endosomes before it is delivered to lysosomes.Identification of the functional activity of the [A-4] amelogenin gene splice product in newborn mouse ameloblasts.Biogenesis of lysosomal membranes.Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis.Lysosomal targeting of P-selectin is mediated by a novel sequence within its cytoplasmic tail.Biosynthesis and intracellular transport of a membrane glycoprotein (plgp57) of the prelysosome compartment.An alpha-helical signal in the cytosolic domain of the interleukin 2 receptor beta chain mediates sorting towards degradation after endocytosisLysosomal amino acid transporter LYAAT-1 in the rat central nervous system: an in situ hybridization and immunohistochemical study.Expression of constitutively active Rab5 uncouples maturation of the Salmonella-containing vacuole from intracellular replication.Degradation of mutant influenza virus hemagglutinins is influenced by cytoplasmic sequences independent of internalization signals.Morphological characterization of pecteneal hyalocytes in the developing quail retina.Analysis of the structural requirements for lysosomal membrane targeting using transferrin receptor chimeras.Sorting of lysosomal membrane glycoproteins lamp-1 and lamp-2 into vesicles distinct from mannose 6-phosphate receptor/gamma-adaptin vesicles at the trans-Golgi network.
P2860
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P2860
The pathway and targeting signal for delivery of the integral membrane glycoprotein LEP100 to lysosomes.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
The pathway and targeting sign ...... coprotein LEP100 to lysosomes.
@ast
The pathway and targeting sign ...... coprotein LEP100 to lysosomes.
@en
type
label
The pathway and targeting sign ...... coprotein LEP100 to lysosomes.
@ast
The pathway and targeting sign ...... coprotein LEP100 to lysosomes.
@en
prefLabel
The pathway and targeting sign ...... coprotein LEP100 to lysosomes.
@ast
The pathway and targeting sign ...... coprotein LEP100 to lysosomes.
@en
P2093
P2860
P356
P1476
The pathway and targeting sign ...... coprotein LEP100 to lysosomes.
@en
P2093
D M Fambrough
J B Martinie
P M Mathews
P2860
P304
P356
10.1083/JCB.118.5.1027
P407
P577
1992-09-01T00:00:00Z