Immunohistochemical loss of succinate dehydrogenase subunit A (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation
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Post-transcriptional dysregulation by miRNAs is implicated in the pathogenesis of gastrointestinal stromal tumor [GIST]SDHA mutations causing a multisystem mitochondrial disease: novel mutations and genetic overlap with hereditary tumorsSyndromic gastrointestinal stromal tumorsSuccinate Dehydrogenase Loss in Familial Paraganglioma: Biochemistry, Genetics, and EpigeneticsNovel uses of immunohistochemistry in the diagnosis and classification of soft tissue tumorsConnecting molecular pathways to hereditary cancer risk syndromesMolecular subtypes of gastrointestinal stromal tumors and their prognostic and therapeutic implications.SDHA related tumorigenesis: a new case series and literature review for variant interpretation and pathogenicity.The progressive fragmentation of the KIT/PDGFRA wild-type (WT) gastrointestinal stromal tumors (GIST)Succinate dehydrogenase deficient gastrointestinal stromal tumors (GISTs) - a review.Succinate dehydrogenase mutation underlies global epigenomic divergence in gastrointestinal stromal tumorIntegrated genomic study of quadruple-WT GIST (KIT/PDGFRA/SDH/RAS pathway wild-type GIST).MDCT features of succinate dehydrogenase (SDH)-deficient gastrointestinal stromal tumours.Succinate dehydrogenase (SDH)-deficient renal carcinoma: a morphologically distinct entity: a clinicopathologic series of 36 tumors from 27 patients.Sarcoma classification: an update based on the 2013 World Health Organization Classification of Tumors of Soft Tissue and Bone.Succinate dehydrogenase-deficient gastrointestinal stromal tumors.A new bispecific antibody targeting non-overlapping epitopes on IGF2: design, in vitro characterization and pharmacokinetics in macaquesA multicenter phase II study of pazopanib in patients with advanced gastrointestinal stromal tumors (GIST) following failure of at least imatinib and sunitinib.Impact of age and gender on tumor related prognosis in gastrointestinal stromal tumors (GIST).Targeting cancer metabolism.A novel germline mutation in SDHA identified in a rare case of gastrointestinal stromal tumor complicated with renal cell carcinoma.The genetic landscape of gastrointestinal stromal tumor lacking KIT and PDGFRA mutations.Succinate dehydrogenase deficiency in pediatric and adult gastrointestinal stromal tumors.Succinate dehydrogenase expression in breast cancer.Gastrointestinal stromal tumors: management of metastatic disease and emerging therapies.Succinate dehydrogenase deficiency is rare in pituitary adenomas.Novel pathways and molecular targets for the treatment of sarcoma.An overview on molecular biology of KIT/PDGFRA wild type (WT) gastrointestinal stromal tumours (GIST).Gastrointestinal stromal tumours: from KIT to succinate dehydrogenase.Newly available antibodies with practical applications in surgical pathology.Gastrointestinal stromal tumors: what do we know now?Toward an improved definition of the genetic and tumor spectrum associated with SDH germ-line mutations.Clinicopathologic study of succinate-dehydrogenase-deficient gastrointestinal stromal tumors: A single-institutional experience in ChinaThe emerging role and targetability of the TCA cycle in cancer metabolism.Biochemical, Molecular, and Clinical Characterization of Succinate Dehydrogenase Subunit A Variants of Unknown Significance."Wild type" GIST: Clinicopathological features and clinical practice.Gastrointestinal stromal tumors (GISTs): SEAP-SEOM consensus on pathologic and molecular diagnosis.P16 overexpression in BRAF-mutated gastrointestinal stromal tumors.Using molecular diagnostic testing to personalize the treatment of patients with gastrointestinal stromal tumors.Functional Effects of Cigarette Smoke-Induced Changes in Airway Smooth Muscle Mitochondrial Morphology.
P2860
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P2860
Immunohistochemical loss of succinate dehydrogenase subunit A (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Immunohistochemical loss of su ...... signals SDHA germline mutation
@ast
Immunohistochemical loss of su ...... signals SDHA germline mutation
@en
type
label
Immunohistochemical loss of su ...... signals SDHA germline mutation
@ast
Immunohistochemical loss of su ...... signals SDHA germline mutation
@en
prefLabel
Immunohistochemical loss of su ...... signals SDHA germline mutation
@ast
Immunohistochemical loss of su ...... signals SDHA germline mutation
@en
P2093
P2860
P1476
Immunohistochemical loss of su ...... signals SDHA germline mutation
@en
P2093
Christopher Lau
Jerzy Lasota
Jonathan Keith Killian
Lee Helman
Marbin Pineda
Markku Miettinen
Paul Meltzer
Robert Walker
Yuelin Jack Zhu
P2860
P304
P356
10.1097/PAS.0B013E3182671178
P407
P50
P577
2013-02-01T00:00:00Z