Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.
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New insights in bilirubin metabolism and their clinical implicationsMultidrug Resistance-Associated Protein 2 Expression Is Upregulated by Adenosine 5'-Triphosphate in Colorectal Cancer Cells and Enhances Their Survival to Chemotherapeutic DrugsNHERF-1 binds to Mrp2 and regulates hepatic Mrp2 expression and functionMontelukast is a potent and durable inhibitor of multidrug resistance protein 2-mediated efflux of taxol and saquinavirXenobiotic, bile acid, and cholesterol transporters: function and regulation.Report of new haplotype for ABCC2 gene: rs17222723 and rs8187718 in cisPhotoaffinity labeling of the multidrug resistance protein 2 (ABCC2/cMOAT) with a photoreactive analog of LTC(4)Expression of BAF57 in ovarian cancer cells and drug sensitivity.Influence of seeding density and extracellular matrix on bile Acid transport and mrp4 expression in sandwich-cultured mouse hepatocytes.Regulation of hepatic ABCC transporters by xenobiotics and in disease states.Interleukin-18 Down-Regulates Multidrug Resistance-Associated Protein 2 Expression through Farnesoid X Receptor Associated with Nuclear Factor Kappa B and Yin Yang 1 in Human Hepatoma HepG2 Cells.Acute and Chronic Administrations of Rheum palmatum Reduced the Bioavailability of Phenytoin in Rats: A New Herb-Drug Interaction.Plasma membrane glutathione transporters and their roles in cell physiology and pathophysiologyFasting induces nuclear factor E2-related factor 2 and ATP-binding Cassette transporters via protein kinase A and Sirtuin-1 in mouse and humanObstetric Obesity is Associated with Neonatal Hyperbilirubinemia with High Prevalence in Native Hawaiians and Pacific Island Women.Central role of mitochondria in drug-induced liver injury.Environmental chemicals as substrates, inhibitors or inducers of drug transporters: implication for toxicokinetics, toxicity and pharmacokinetics.Renal transport of organic anions and cations.Hormonal regulation of hepatic drug biotransformation and transport systems.Phase 0 and phase III transport in various organs: combined concept of phases in xenobiotic transport and metabolism.Gene replacement therapy for genetic hepatocellular jaundice.New insights in the biology of ABC transporters ABCC2 and ABCC3: impact on drug disposition.Regulation of drug transporter expression and function in the placenta.Influence of multidrug resistance and drug transport proteins on chemotherapy drug metabolism.Hepatic drug transporters: the journey so far.Modulators of the human ABCC2: hope from natural sources?Efflux Transporters Regulate Arsenite Induced Genotoxicity in Double Negative and Double Positive T Cells.ABCC2 (1249G > A) polymorphism implicates altered transport activity for sorafenib.A cisplatin-resistant head and neck cancer cell line with cytoplasmic p53(mut) exhibits ATP-binding cassette transporter upregulation and high glutathione levels.A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies.Reversal effect of BM-cyclin 1 on multidrug resistance by down-regulating MRP2 in BALB/C nude mice bearing C-A120 cells.The therapeutic potential of targeting ABC transporters to combat multi-drug resistance.Phase I and II metabolism and MRP2-mediated export of bosentan in a MDCKII-OATP1B1-CYP3A4-UGT1A1-MRP2 quadruple-transfected cell line.Posttranslational regulation of Abcc2 expression by SUMOylation system.Effect of nine diets on xenobiotic transporters in livers of mice.Serum serotonin reduced the expression of hepatic transporter Mrp2 and P-gp via regulating nuclear receptor CAR in PI-IBS rats.New perspectives of cobalt tris(bipyridine) system: anti-cancer effect and its collateral sensitivity towards multidrug-resistant (MDR) cancers.Expression of the Abca-subfamily of genes in Abcc6-/- mice--upregulation of Abca4.Ischemia-reperfusion-inducible protein modulates cell sensitivity to anticancer drugs by regulating activity of efflux transporter.A membrane vesicle-based assay to enable prediction of human biliary excretion.
P2860
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P2860
Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.
@ast
Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.
@en
type
label
Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.
@ast
Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.
@en
prefLabel
Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.
@ast
Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.
@en
P2093
P2860
P356
P1476
Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.
@en
P2093
Gabriele Jedlitschky
Heyo K Kroemer
Ulrich Hoffmann
P2860
P304
P356
10.1517/17425255.2.3.351
P407
P577
2006-06-01T00:00:00Z