The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome.
about
Immunoproteasome deficiency modifies the alternative pathway of NFκB signalingProteasomal interference prevents zona pellucida penetration and fertilization in mammalsIFN-gamma-induced immune adaptation of the proteasome system is an accelerated and transient responsePI31 is a modulator of proteasome formation and antigen processingMHC class I antigen processing and presenting machinery: organization, function, and defects in tumor cellsImmunoproteasomes: structure, function, and antigen presentationTargeting the ubiquitin-proteasome system in heart disease: the basis for new therapeutic strategiesMolecular architecture and assembly of the eukaryotic proteasomeThe immunoproteasome and viral infection: a complex regulator of inflammationProteasome assemblyImmunoproteasome overexpression underlies the pathogenesis of thyroid oncocytes and primary hypothyroidism: studies in humans and mice.20S immunoproteasomes remove formaldehyde-damaged cytoplasmic proteins suppressing caspase-independent cell death.Computational analysis and modeling of cleavage by the immunoproteasome and the constitutive proteasomeDeletion of immunoproteasome subunits imprints on the transcriptome and has a broad impact on peptides presented by major histocompatibility complex I molecules.Unexpected role for the immunoproteasome subunit LMP2 in antiviral humoral and innate immune responses.Beta 2 subunit propeptides influence cooperative proteasome assembly.Impaired expression of proteasome subunits and human leukocyte antigens class I in human colon cancer cells.Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules.Proteasome functioning in breast cancer: connection with clinical-pathological factorsCross-presentation of synthetic long peptides by human dendritic cells: a process dependent on ERAD component p97/VCP but Not sec61 and/or Derlin-1.Elucidating the catalytic subunit composition of distinct proteasome subtypes: a crosslinking approach employing bifunctional activity-based probes.Immunoproteasome deficiency protects in the retina after optic nerve crush.Immunoproteasome subunit LMP2 expression is deregulated in Sjogren's syndrome but not in other autoimmune disorders.Generation of major histocompatibility complex class I antigens: functional interplay between proteasomes and TPPII.SAMe prevents the induction of the immunoproteasome and preserves the 26S proteasome in the DDC-induced MDB mouse model.Changes in the Proteasome Pool during Malignant Transformation of Mouse Liver CellsEnhanced expression of interferon-gamma-induced antigen-processing machinery components in a spontaneously occurring cancer.Ethanol and hepatitis C virus suppress peptide-MHC class I presentation in hepatocytes by altering proteasome function.Denervation-Induced Activation of the Standard Proteasome and ImmunoproteasomeProteasome function is not impaired in healthy aging of the lung.Interferon-gamma, the functional plasticity of the ubiquitin-proteasome system, and MHC class I antigen processing.Inhibition of immunoproteasome reduces infarction volume and attenuates inflammatory reaction in a rat model of ischemic stroke.Efficient generation of a hepatitis B virus cytotoxic T lymphocyte epitope requires the structural features of immunoproteasomes.Immunoproteasome assembly: cooperative incorporation of interferon gamma (IFN-gamma)-inducible subunitsThe sequence alteration associated with a mutational hotspot in p53 protects cells from lysis by cytotoxic T lymphocytes specific for a flanking peptide epitope.The proteasome immunosubunit multicatalytic endopeptidase complex-like 1 is a T-cell-intrinsic factor influencing homeostatic expansionMismatch in epitope specificities between IFNγ inflamed and uninflamed conditions leads to escape from T lymphocyte killing in melanoma.A cytomegalovirus inhibitor of gamma interferon signaling controls immunoproteasome induction.Molecular mechanisms of IFN-gamma to up-regulate MHC class I antigen processing and presentation.Effects of ethanol on the proteasome interacting proteins.
P2860
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P2860
The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
The subunits MECL-1 and LMP2 a ...... ation into the 20S proteasome.
@ast
The subunits MECL-1 and LMP2 a ...... ation into the 20S proteasome.
@en
type
label
The subunits MECL-1 and LMP2 a ...... ation into the 20S proteasome.
@ast
The subunits MECL-1 and LMP2 a ...... ation into the 20S proteasome.
@en
prefLabel
The subunits MECL-1 and LMP2 a ...... ation into the 20S proteasome.
@ast
The subunits MECL-1 and LMP2 a ...... ation into the 20S proteasome.
@en
P2093
P2860
P356
P1476
The subunits MECL-1 and LMP2 a ...... ation into the 20S proteasome.
@en
P2093
M Groettrup
P M Kloetzel
R Stohwasser
S Standera
P2860
P304
P356
10.1073/PNAS.94.17.8970
P407
P577
1997-08-01T00:00:00Z