Host pathways important for Coxiella burnetii infection revealed by genome-wide RNA interference screening. - Test2 - elhamkhani - TriplyDB

Host pathways important for Coxiella burnetii infection revealed by genome-wide RNA interference screening.

Host pathways important for Coxiella burnetii infection revealed by genome-wide RNA interference screening.

http://www.wikidata.org/entity/Q36576675

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Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recycling Role of the Retromer Complex in Neurodegenerative Diseases Q28069944 Space: A Final Frontier for Vacuolar Pathogens Alterations of the Coxiella burnetii Replicative Vacuole Membrane Integrity and Interplay with the Autophagy Pathway.Essential role for the response regulator PmrA in Coxiella burnetii type 4B secretion and colonization of mammalian host cells.Coxiella burnetii type IV secretion-dependent recruitment of macrophage autophagosomes.Manipulation of Host Cholesterol by Obligate Intracellular Bacteria.Host-directed antimicrobial drugs with broad-spectrum efficacy against intracellular bacterial pathogens.Molecular pathogenesis of the obligate intracellular bacterium Coxiella burnetii Identification of novel Coxiella burnetii Icm/Dot effectors and genetic analysis of their involvement in modulating a mitogen-activated protein kinase pathway.Retromer: a master conductor of endosome sorting.Vaccination against Q fever for biodefense and public health indications.Coxiella burnetii effector proteins that localize to the parasitophorous vacuole membrane promote intracellular replication.A screen of Coxiella burnetii mutants reveals important roles for Dot/Icm effectors and host autophagy in vacuole biogenesis Coxiella burnetii Phagocytosis Is Regulated by GTPases of the Rho Family and the RhoA Effectors mDia1 and ROCK The Effector Cig57 Hijacks FCHO-Mediated Vesicular Trafficking to Facilitate Intracellular Replication of Coxiella burnetii Biogenesis of the lysosome-derived vacuole containing Coxiella burnetii.Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA.Effector Protein Cig2 Decreases Host Tolerance of Infection by Directing Constitutive Fusion of Autophagosomes with the Coxiella-Containing Vacuole.Coxiella burnetii effector CvpB modulates phosphoinositide metabolism for optimal vacuole development.Coxiella burnetii effector protein subverts clathrin-mediated vesicular trafficking for pathogen vacuole biogenesis.High-Content Imaging Reveals Expansion of the Endosomal Compartment during Coxiella burnetii Parasitophorous Vacuole Maturation Structural basis for the hijacking of endosomal sorting nexin proteins by Chlamydia trachomatis Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction.Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection.A Rab-centric perspective of bacterial pathogen-occupied vacuoles.Master manipulators: an update on Legionella pneumophila Icm/Dot translocated substrates and their host targets Dining in: intracellular bacterial pathogen interplay with autophagy.At the crossroads: communication of bacteria-containing vacuoles with host organelles.Interactions between the Coxiella burnetii parasitophorous vacuole and the endoplasmic reticulum involve the host protein ORP1L.Right on Q: genetics begin to unravel Coxiella burnetii host cell interactions.Avoidance and Subversion of Eukaryotic Homeostatic Autophagy Mechanisms by Bacterial Pathogens.Targeting mitochondria: how intravacuolar bacterial pathogens manipulate mitochondria.Quantitative Dextran Trafficking to the Coxiella burnetii Parasitophorous Vacuole.Applying Fluorescence Resonance Energy Transfer (FRET) to Examine Effector Translocation Efficiency by Coxiella burnetii during siRNA Silencing.A repeat motif on a Coxiella effector protein facilitates apoptosis inhibition Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling.Measuring pH of the Coxiella burnetii Parasitophorous Vacuole.Mechanisms of action of Coxiella burnetii effectors inferred from host-pathogen protein interactions.

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P2860

Host pathways important for Coxiella burnetii infection revealed by genome-wide RNA interference screening.

http://www.wikidata.org/entity/Q36576675

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2013 nî lūn-bûn

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Host pathways important for Co ...... de RNA interference screening.

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Craig R Roy

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Hayley J Newton

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Hervé Agaisse

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Justin A McDonough

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Rachel Swiss

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Scott Klum

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P2860

Three novel proteins of the syntaxin/SNAP-25 family

Syntaxin 18, a SNAP receptor that functions in the endoplasmic reticulum, intermediate compartment, and cis-Golgi vesicle trafficking

CLN3 protein regulates lysosomal pH and alters intracellular processing of Alzheimer's amyloid-beta protein precursor and cathepsin D in human cells

Syntaxin 17 is abundant in steroidogenic cells and implicated in smooth endoplasmic reticulum membrane dynamics

Syntaxin 17 cycles between the ER and ERGIC and is required to maintain the architecture of ERGIC and Golgi

A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion

Ankyrin repeat proteins comprise a diverse family of bacterial type IV effectors

Host cell-free growth of the Q fever bacterium Coxiella burnetii

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