A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels.
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Two-pore Domain Potassium Channels in AstrocytesPolymodal activation of the TREK-2 K2P channel produces structurally distinct open statesMarkov modeling reveals novel intracellular modulation of the human TREK-2 selectivity filter.Dominant-Negative Effect of a Missense Variant in the TASK-2 (KCNK5) K+ Channel Associated with Balkan Endemic Nephropathy.Selective Small Molecule Activators of TREK-2 Channels Stimulate Dorsal Root Ganglion c-Fiber Nociceptor Two-Pore-Domain Potassium Channel Currents and Limit Calcium Influx.Unambiguous observation of blocked states reveals altered, blocker-induced, cardiac ryanodine receptor gatingAge-dependent diastolic heart failure in an in vivo Drosophila model.Sodium permeable and "hypersensitive" TREK-1 channels cause ventricular tachycardia.K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site.Gating Charge Calculations by Computational Electrophysiology Simulations.Gating, Regulation, and Structure in K2P K+ Channels: In Varietate Concordia?Ion Channel Activity of Vpu Proteins Is Conserved throughout Evolution of HIV-1 and SIV.Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel.The effects of stretch activation on ionic selectivity of the TREK-2 K2P K+ channel.Extended beta distributions open the access to fast gating in bilayer experiments-assigning the voltage-dependent gating to the selectivity filter.The gating mechanism in cyclic nucleotide-gated ion channels.Global versus local mechanisms of temperature sensing in ion channels.Conversion of an instantaneous activating K+ channel into a slow activating inward rectifier.GI-530159, a novel, selective, mechanosensitive two-pore-domain potassium (K2P ) channel opener, reduces rat dorsal root ganglion neuron excitability.A single NaK channel conformation is not enough for non-selective ion conduction.Exploring the Viral Channel KcvPBCV-1 Function via Computation.TMEM150C/Tentonin3 Is a Regulator of Mechano-gated Ion Channels.Voltage gating of mechanosensitive PIEZO channels.Mechanism of Mechanosensitive Gating of the TREK-2 Potassium Channel.TRESK background potassium channel is not gated at the helix bundle crossing near the cytoplasmic end of the pore.Site-specific ion occupation in the selectivity filter causes voltage-dependent gating in a viral K+ channel.
P2860
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P2860
A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels.
description
2016 nî lūn-bûn
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2016年の論文
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2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels.
@ast
A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels.
@en
type
label
A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels.
@ast
A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels.
@en
prefLabel
A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels.
@ast
A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels.
@en
P2093
P2860
P50
P1433
P1476
A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels
@en
P2093
Bert L de Groot
Ehsan Nematian-Ardestani
Giovanna Bucci
Markus Rapedius
Sönke Cordeiro
Thomas Baukrowitz
P2860
P304
P356
10.1016/J.CELL.2016.02.002
P407
P577
2016-02-01T00:00:00Z