Proteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liver
about
Chaperoning to the metabolic party: The emerging therapeutic role of heat-shock proteins in obesity and type 2 diabetesNck1 depletion induces activation of the PI3K/Akt pathway by attenuating PTP1B protein expression.Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity.Proteasome dysfunction mediates high glucose-induced apoptosis in rodent beta cells and human isletsEffect of enriching the diet with menhaden oil or daily treatment with resolvin D1 on neuropathy in a mouse model of type 2 diabetes.Proteasome Dysfunction Associated to Oxidative Stress and Proteotoxicity in Adipocytes Compromises Insulin Sensitivity in Human Obesity.PA28 modulates antigen processing and viral replication during coxsackievirus B3 infection.Impact of ER protein homeostasis on metabolism.Proteasome activators, PA28γ and PA200, play indispensable roles in male fertility.Nitric oxide differentially affects proteasome activator 28 after arterial injury in type 1 and type 2 diabetic ratsThe REGγ proteasome regulates hepatic lipid metabolism through inhibition of autophagy.Association of obesity with proteasomal gene polymorphisms in children.Oncogenic mutations and dysregulated pathways in obesity-associated hepatocellular carcinoma.Genome-wide association study identifies African-ancestry specific variants for metabolic syndrome.The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes.Impaired proteostasis: role in the pathogenesis of diabetes mellitus.Endoplasmic reticulum stress in obesity and obesity-related disorders: An expanded view.Changes in glucose transporter expression and nitric oxide production are associated with liver injury in diabetes.Hyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in Adipocytes.The Pathogenesis of Obesity-Associated Adipose Tissue Inflammation.Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.Aortic dysfunction in metabolic syndrome mediated by perivascular adipose tissue TNFα and NOX2 dependent pathway.Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice.Sodium 4-Phenylbutyrate Attenuates Myocardial Reperfusion Injury by Reducing the Unfolded Protein Response.Cellular senescence: Implications for metabolic disease.Effect of Fish Oil vs. Resolvin D1, E1, Methyl Esters of Resolvins D1 or D2 on Diabetic Peripheral Neuropathy.Liver function and dysfunction - a unique window into the physiological reach of ER stress and the unfolded protein response.Unexpected metabolic disorders induced by endocrine disruptors in Xenopus tropicalis provide new lead for understanding amphibian decline.Inhibin βE (INHBE) is a possible insulin resistance-associated hepatokine identified by comprehensive gene expression analysis in human liver biopsy samples.Pluripotent Stem Cell Model of Nakajo-Nishimura Syndrome Untangles Proinflammatory Pathways Mediated by Oxidative Stress.JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies.Icariin Ameliorates Palmitate-Induced Insulin Resistance Through Reducing Thioredoxin-Interacting Protein (TXNIP) and Suppressing ER Stress in C2C12 Myotubes
P2860
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P2860
Proteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liver
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Proteasome dysfunction mediate ...... nsulin resistance in the liver
@ast
Proteasome dysfunction mediate ...... nsulin resistance in the liver
@en
type
label
Proteasome dysfunction mediate ...... nsulin resistance in the liver
@ast
Proteasome dysfunction mediate ...... nsulin resistance in the liver
@en
prefLabel
Proteasome dysfunction mediate ...... nsulin resistance in the liver
@ast
Proteasome dysfunction mediate ...... nsulin resistance in the liver
@en
P2093
P2860
P356
P1433
P1476
Proteasome dysfunction mediate ...... nsulin resistance in the liver
@en
P2093
Hiroaki Takayama
Hirofumi Misu
Hiroto Hayashi
Kaito Iwayama
Kazuhide Ishikura
Keiji Tanaka
Ken-ichiro Kato
Kosuke R Shima
Kunpei Tokuyama
P2860
P304
P356
10.2337/DB11-1652
P407
P577
2012-12-03T00:00:00Z