Berberine protects rat heart from ischemia/reperfusion injury via activating JAK2/STAT3 signaling and attenuating endoplasmic reticulum stress. - Test2 - elhamkhani - TriplyDB

Berberine protects rat heart from ischemia/reperfusion injury via activating JAK2/STAT3 signaling and attenuating endoplasmic reticulum stress.

Berberine protects rat heart from ischemia/reperfusion injury via activating JAK2/STAT3 signaling and attenuating endoplasmic reticulum stress.

http://www.wikidata.org/entity/Q36644283

about

The Natural Occurring Compounds Targeting Endoplasmic Reticulum Stress Rhizoma Coptidis: A Potential Cardiovascular Protective Agent Unfolded protein response plays a critical role in heart damage after myocardial ischemia/reperfusion in rats Melatonin ameliorates myocardial ischemia/reperfusion injury in type 1 diabetic rats by preserving mitochondrial function: role of AMPK-PGC-1α-SIRT3 signaling.Lowering serum lipids via PCSK9-targeting drugs: current advances and future perspectives.Naringenin ameliorates hypoxia/reoxygenation-induced endoplasmic reticulum stress-mediated apoptosis in H9c2 myocardial cells: involvement in ATF6, IRE1α and PERK signaling activation.Diallyl trisulfide ameliorates myocardial ischemia-reperfusion injury by reducing oxidative stress and endoplasmic reticulum stress-mediated apoptosis in type 1 diabetic rats: role of SIRT1 activation.Peroxisome proliferator-activated receptor γ (PPARγ) mediates the protective effect of quercetin against myocardial ischemia-reperfusion injury via suppressing the NF-κB pathway.Bisoprolol protects myocardium cells against ischemia/reperfusion injury by attenuating unfolded protein response in rats.Diallyl trisulfide exerts cardioprotection against myocardial ischemia-reperfusion injury in diabetic state, role of AMPK-mediated AKT/GSK-3β/HIF-1α activation.Inhibitors of soluble epoxide hydrolase minimize ischemia-reperfusion-induced cardiac damage in normal, hypertensive, and diabetic rats.Protective effects of carnosic acid against mitochondria-mediated injury in H9c2 cardiomyocytes induced by hypoxia/reoxygenation.Eriodictyol Attenuates Myocardial Ischemia-Reperfusion Injury through the Activation of JAK2.Berberine confers neuroprotection in coping with focal cerebral ischemia by targeting inflammatory cytokines.

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P2860

Berberine protects rat heart from ischemia/reperfusion injury via activating JAK2/STAT3 signaling and attenuating endoplasmic reticulum stress.

http://www.wikidata.org/entity/Q36644283

description

2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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Acta Pharmacologica Sinica

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Berberine protects rat heart f ...... endoplasmic reticulum stress.

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Bin Zhang

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Bo Jiang

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Guo-long Zhao

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Li-ming Yu

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Meng-en Zhai

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Shi-qiang Yu

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Wei-xun Duan

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Wen-li Gao

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Xu-dong Liu

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Yun Wang

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P2860

Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor

Butanol fraction containing berberine or related compound from nexrutine inhibits NFkappaB signaling and induces apoptosis in prostate cancer cells

Endoplasmic reticulum stress and diabetic cardiomyopathy

Acyloxy nitroso compounds inhibit LIF signaling in endothelial cells and cardiac myocytes: evidence that STAT3 signaling is redox-sensitive

JAK2/STAT3 activation by melatonin attenuates the mitochondrial oxidative damage induced by myocardial ischemia/reperfusion injury

Janus kinases and their role in growth and disease.

Integrative analysis of differential miRNA and functional study of miR-21 by seed-targeting inhibition in multiple myeloma cells in response to berberine.

STAT proteins and transcriptional responses to extracellular signals.

Vulnerable substrate and multiple ion channel disorder in a diseased heart will be new targets for antiarrhythmic therapy.

The potential of alkaloids in drug discovery.

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354-367

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10.1038/APS.2015.136

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3

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37

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reperfusion injury

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