A soluble activin type IIA receptor induces bone formation and improves skeletal integrity.
about
Regulation of osteoblastogenesis and osteoclastogenesis by the other reproductive hormones, Activin and InhibinTGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formationActivin A inhibits RANKL-mediated osteoclast formation, movement and function in murine bone marrow macrophage cultures.Bone morphogenetic protein-3b (BMP-3b) is expressed in adipocytes and inhibits adipogenesis as a unique complexAdvancing treatment for metastatic bone cancer: consensus recommendations from the Second Cambridge Conference.Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone diseaseUpdate in new anabolic therapies for osteoporosisActivin-A signaling promotes epithelial-mesenchymal transition, invasion, and metastatic growth of breast cancerThe effects of GATA-1 and NF-E2 deficiency on bone biomechanical, biochemical, and mineral properties.Multiple myeloma mesenchymal stromal cells: Contribution to myeloma bone disease and therapeuticsGrowth factor control of bone mass.A roadmap to the brittle bones of cystic fibrosis.An activin receptor IIA ligand trap promotes erythropoiesis resulting in a rapid induction of red blood cells and haemoglobinSotatercept in patients with osteolytic lesions of multiple myeloma.Mechanisms inducing low bone density in Duchenne muscular dystrophy in mice and humans.Development of novel activin-targeted therapeutics.Loss of BMPR2 leads to high bone mass due to increased osteoblast activityBone anabolic agents for the treatment of multiple myeloma.BMP3 suppresses osteoblast differentiation of bone marrow stromal cells via interaction with Acvr2b.Update on bone anabolics in osteoporosis treatment: rationale, current status, and perspectivesNew treatment modalities in osteoporosis.Administration of soluble activin receptor 2B increases bone and muscle mass in a mouse model of osteogenesis imperfectaEffects of Age and Estrogen on Skeletal Gene Expression in Humans as Assessed by RNA Sequencing.A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength.Treatment with soluble activin type IIB-receptor improves bone mass and strength in a mouse model of Duchenne muscular dystrophy.Virtual High-Throughput Screening To Identify Novel Activin Antagonists.Impact of Gap Junctional Intercellular Communication on MLO-Y4 Sclerostin and Soluble Factor Expression.Transforming Growth Factor-β Family Ligands Can Function as Antagonists by Competing for Type II Receptor Binding.Effects of the activin A-myostatin-follistatin system on aging bone and muscle progenitor cellsCellular mechanisms of multiple myeloma bone diseaseBone and skeletal muscle: neighbors with close tiesActivin A suppresses osteoblast mineralization capacity by altering extracellular matrix (ECM) composition and impairing matrix vesicle (MV) production.Activin signaling as an emerging target for therapeutic interventionsReproductive hormones in breast cancer bone metastasis: The role of inhibins.Development of insulin-producing cells from primitive biologic precursors.Investigational anabolic therapies for osteoporosis.Bone metastases: molecular mechanisms and novel therapeutic interventions.Antagonism of activin by activin chimeras.TGF-β in the Bone Microenvironment: Role in Breast Cancer Metastases.Prevention and treatment of myeloma bone disease.
P2860
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P2860
A soluble activin type IIA receptor induces bone formation and improves skeletal integrity.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A soluble activin type IIA rec ...... d improves skeletal integrity.
@ast
A soluble activin type IIA rec ...... d improves skeletal integrity.
@en
type
label
A soluble activin type IIA rec ...... d improves skeletal integrity.
@ast
A soluble activin type IIA rec ...... d improves skeletal integrity.
@en
prefLabel
A soluble activin type IIA rec ...... d improves skeletal integrity.
@ast
A soluble activin type IIA rec ...... d improves skeletal integrity.
@en
P2093
P2860
P356
P1476
A soluble activin type IIA rec ...... d improves skeletal integrity.
@en
P2093
Asya Grinberg
Brendan Haigis
Deanna Smith
Eileen Pobre
Eric D Werner
Ernesto Canalis
Jasbir Seehra
Jeffrey Ucran
Kathryn W Underwood
Lisa Stadmeyer
P2860
P304
P356
10.1073/PNAS.0711263105
P407
P577
2008-05-06T00:00:00Z