Sarcolipin protein interaction with sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) is distinct from phospholamban protein, and only sarcolipin can promote uncoupling of the SERCA pump.
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The Structural Basis for Phospholamban Inhibition of the Calcium Pump in Sarcoplasmic ReticulumCardiac specific expression of threonine 5 to alanine mutant sarcolipin results in structural remodeling and diastolic dysfunctionThe role of skeletal-muscle-based thermogenic mechanisms in vertebrate endothermyStructural dynamics and conformational equilibria of SERCA regulatory proteins in membranes by solid-state NMR restrained simulations.S-palmitoylation and s-oleoylation of rabbit and pig sarcolipin.Co-expression of SERCA isoforms, phospholamban and sarcolipin in human skeletal muscle fibersAtomic-level mechanisms for phospholamban regulation of the calcium pump.Sarcolipin overexpression improves muscle energetics and reduces fatigue.Sarcolipin Is a Key Determinant of the Basal Metabolic Rate, and Its Overexpression Enhances Energy Expenditure and Resistance against Diet-induced Obesity.The N Terminus of Sarcolipin Plays an Important Role in Uncoupling Sarco-endoplasmic Reticulum Ca2+-ATPase (SERCA) ATP Hydrolysis from Ca2+ TransportSpecific Activation of the Plant P-type Plasma Membrane H+-ATPase by Lysophospholipids Depends on the Autoinhibitory N- and C-terminal Domains.Reduced efficiency of sarcolipin-dependent respiration in myocytes from humans with severe obesity.Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice.Sarcolipin is a novel regulator of muscle metabolism and obesity.Phosphorylated phospholamban stabilizes a compact conformation of the cardiac calcium-ATPase.Ca(2+)/H (+) exchange, lumenal Ca(2+) release and Ca (2+)/ATP coupling ratios in the sarcoplasmic reticulum ATPaseThe regulation of sarco(endo)plasmic reticulum calcium-ATPases (SERCA).Salsalate Activates Skeletal Muscle Thermogenesis and Protects Mice from High-Fat Diet Induced Metabolic DysfunctionPhospholamban and sarcolipin: Are they functionally redundant or distinct regulators of the Sarco(Endo)Plasmic Reticulum Calcium ATPase?Role of SERCA Pump in Muscle Thermogenesis and Metabolism.The complementary and divergent roles of uncoupling proteins 1 and 3 in thermoregulation.Sarcolipin: A Key Thermogenic and Metabolic Regulator in Skeletal Muscle.Increased Reliance on Muscle-based Thermogenesis upon Acute Minimization of Brown Adipose Tissue Function.Sarcolipin and phospholamban inhibit the calcium pump by populating a similar metal ion-free intermediate state.Skeletal Muscle Thermogenesis and Its Role in Whole Body Energy Metabolism.Sarcolipin Promotes Uncoupling of the SERCA Ca2+ Pump by Inducing a Structural Rearrangement in the Energy-Transduction Domain.Muscle Non-shivering Thermogenesis and Its Role in the Evolution of Endothermy.Conformational memory in the association of the transmembrane protein phospholamban with the sarcoplasmic reticulum calcium pump SERCA.Both brown adipose tissue and skeletal muscle thermogenesis processes are activated during mild to severe cold adaptation in mice.Misregulation of calcium-handling proteins promotes hyperactivation of calcineurin-NFAT signaling in skeletal muscle of DM1 mice.Sarcolipin Makes Heat, but Is It Adaptive Thermogenesis?The Role of Sarcolipin in Muscle Non-shivering Thermogenesis
P2860
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P2860
Sarcolipin protein interaction with sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) is distinct from phospholamban protein, and only sarcolipin can promote uncoupling of the SERCA pump.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Sarcolipin protein interaction ...... uncoupling of the SERCA pump.
@ast
Sarcolipin protein interaction ...... uncoupling of the SERCA pump.
@en
type
label
Sarcolipin protein interaction ...... uncoupling of the SERCA pump.
@ast
Sarcolipin protein interaction ...... uncoupling of the SERCA pump.
@en
prefLabel
Sarcolipin protein interaction ...... uncoupling of the SERCA pump.
@ast
Sarcolipin protein interaction ...... uncoupling of the SERCA pump.
@en
P2093
P2860
P356
P1476
Sarcolipin protein interaction ...... e uncoupling of the SERCA pump
@en
P2093
Danesh H Sopariwala
Naresh C Bal
Sana A Shaikh
Sanjaya K Sahoo
P2860
P304
P356
10.1074/JBC.M112.436915
P407
P577
2013-01-22T00:00:00Z