Reactive astrocytes secrete lcn2 to promote neuron death. - Test2 - elhamkhani - TriplyDB

Reactive astrocytes secrete lcn2 to promote neuron death.

Reactive astrocytes secrete lcn2 to promote neuron death.

http://www.wikidata.org/entity/Q36673303

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Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation Intercellular cross-talk in intracerebral hemorrhage Human stem cell-derived spinal cord astrocytes with defined mature or reactive phenotypes Partial loss of TDP-43 function causes phenotypes of amyotrophic lateral sclerosis.Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats Gene profiling of human induced pluripotent stem cell-derived astrocyte progenitors following spinal cord engraftment.Lipocalin-2 protein deficiency ameliorates experimental autoimmune encephalomyelitis: the pathogenic role of lipocalin-2 in the central nervous system and peripheral lymphoid tissues.Chronic diazepam administration increases the expression of Lcn2 in the CNS.Lipocalin-2 Acts as a Neuroinflammatogen in Lipopolysaccharide-injected Mice.Profiling the genes affected by pathogenic TDP-43 in astrocytes Bone morphogenetic protein 7 regulates reactive gliosis in retinal astrocytes and Müller glia.Neuronal production of lipocalin-2 as a help-me signal for glial activation Lipocalin-2 deficiency attenuates neuroinflammation and brain injury after transient middle cerebral artery occlusion in mice Lipocalin 2 modulates the cellular response to amyloid beta.Genetic heterogeneity of amyotrophic lateral sclerosis: implications for clinical practice and research.Hu antigen R (HuR) is a positive regulator of the RNA-binding proteins TDP-43 and FUS/TLS: implications for amyotrophic lateral sclerosis.Cerebrospinal fluid biomarker candidates associated with human WNV neuroinvasive disease.CCR5 knockout prevents neuronal injury and behavioral impairment induced in a transgenic mouse model by a CXCR4-using HIV-1 glycoprotein 120 Induction of COX-2-PGE2 synthesis by activation of the MAPK/ERK pathway contributes to neuronal death triggered by TDP-43-depleted microglia.Elevated mRNA-levels of distinct mitochondrial and plasma membrane Ca(2+) transporters in individual hypoglossal motor neurons of endstage SOD1 transgenic mice.Lipocalin-2 as an Infection-Related Biomarker to Predict Clinical Outcome in Ischemic Stroke Role of lipocalin-2 in brain injury after intracerebral hemorrhage.Enteric glia mediate neuron death in colitis through purinergic pathways that require connexin-43 and nitric oxide.Lipocalin-2 is increased in progressive multiple sclerosis and inhibits remyelination A cellular star atlas: using astrocytes from human pluripotent stem cells for disease studies Use of biomarkers in ALS drug development and clinical trials Role of Lipocalin-2 in Thrombin-Induced Brain Injury Neutrophil Gelatinase-Associated Lipocalin and its Receptors in Alzheimer's Disease (AD) Brain Regions: Differential Findings in AD with and without Depression.Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration.T Lymphocytes and Inflammatory Mediators in the Interplay between Brain and Blood in Alzheimer's Disease: Potential Pools of New Biomarkers.Ezrin expression and cell survival regulation in colorectal cancer Colibactin Contributes to the Hypervirulence of pks+ K1 CC23 Klebsiella pneumoniae in Mouse Meningitis Infections.Proteome of brain glia: the molecular basis of diverse glial phenotypes.Astrocyte Transcriptome from the Mecp2(308)-Truncated Mouse Model of Rett Syndrome.TDP-43-The key to understanding amyotrophic lateral sclerosis.The established and emerging roles of astrocytes and microglia in amyotrophic lateral sclerosis and frontotemporal dementia Switching from astrocytic neuroprotection to neurodegeneration by cytokine stimulation.Help-me signaling: Non-cell autonomous mechanisms of neuroprotection and neurorecovery.Lipocalin-2 enhances angiogenesis in rat brain endothelial cells via reactive oxygen species and iron-dependent mechanisms.Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.

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P2860

Reactive astrocytes secrete lcn2 to promote neuron death.

http://www.wikidata.org/entity/Q36673303

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2013年论文

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2013年论文

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name

Reactive astrocytes secrete lcn2 to promote neuron death.

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Reactive astrocytes secrete lcn2 to promote neuron death.

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Reactive astrocytes secrete lcn2 to promote neuron death.

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Reactive astrocytes secrete lcn2 to promote neuron death.

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Reactive astrocytes secrete lcn2 to promote neuron death.

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Reactive astrocytes secrete lcn2 to promote neuron death.

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PNAS.1218497110

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Proceedings of the National Academy of Sciences of the United States of America

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Reactive astrocytes secrete lcn2 to promote neuron death.

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P2093

Bo Huang

http://www.w3.org/2001/XMLSchema#string

Cao Huang

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Fang Li

http://www.w3.org/2001/XMLSchema#string

Fangfang Bi

http://www.w3.org/2001/XMLSchema#string

Guang Qiu

http://www.w3.org/2001/XMLSchema#string

Hongxia Zhou

http://www.w3.org/2001/XMLSchema#string

Jianbin Tong

http://www.w3.org/2001/XMLSchema#string

Qinxue Wu

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Robert Bowser

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Xu-Gang Xia

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P2860

Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

FUS transgenic rats develop the phenotypes of amyotrophic lateral sclerosis and frontotemporal lobar degeneration

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

Functional analysis of the rat N-methyl-D-aspartate receptor 2A promoter: multiple transcription starts points, positive regulation by Sp factors, and translational regulation

Lipocalin-2 is an autocrine mediator of reactive astrocytosis

The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptake

A cell-surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptake

Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1

Functional recovery in traumatic spinal cord injury after transplantation of multineurotrophin-expressing glial-restricted precursor cells.

Disruption of the Lcn2 gene in mice suppresses primary mammary tumor formation but does not decrease lung metastasis.

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