The Tec kinase ITK regulates thymic expansion, emigration, and maturation of γδ NKT cells
about
ITK tunes IL-4-induced development of innate memory CD8+ T cells in a γδ T and invariant NKT cell-independent manner.ITK signalling via the Ras/IRF4 pathway regulates the development and function of Tr1 cells.Innate PLZF+CD4+ αβ T cells develop and expand in the absence of Itk.Development of innate CD4+ and CD8+ T cells in Itk-deficient mice is regulated by distinct pathwaysImmunodeficiency and immune dysregulation associated with proximal defects of T cell receptor signaling.Itk signals promote neuroinflammation by regulating CD4+ T-cell activation and trafficking.IL-2-inducible T cell kinase tunes T regulatory cell development and is required for suppressive functionThe role of LAT-PLCγ1 interaction in γδ T cell development and homeostasis.Innate memory T cells.CD28 controls the development of innate-like CD8+ T cells by promoting the functional maturation of NKT cells.Differential dependence on nuclear factor-κB-inducing kinase among natural killer T-cell subsets in their development.
P2860
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P2860
The Tec kinase ITK regulates thymic expansion, emigration, and maturation of γδ NKT cells
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
The Tec kinase ITK regulates thymic expansion, emigration, and maturation of γδ NKT cells
@ast
The Tec kinase ITK regulates thymic expansion, emigration, and maturation of γδ NKT cells
@en
type
label
The Tec kinase ITK regulates thymic expansion, emigration, and maturation of γδ NKT cells
@ast
The Tec kinase ITK regulates thymic expansion, emigration, and maturation of γδ NKT cells
@en
prefLabel
The Tec kinase ITK regulates thymic expansion, emigration, and maturation of γδ NKT cells
@ast
The Tec kinase ITK regulates thymic expansion, emigration, and maturation of γδ NKT cells
@en
P2093
P2860
P356
P1476
The Tec kinase ITK regulates thymic expansion, emigration, and maturation of γδ NKT cells
@en
P2093
Amanda L Prince
Catherine C Yin
John W Evans
Katelyn E Sylvia
Kavitha Narayan
Leslie J Berg
Ok Hyun Cho
P2860
P304
P356
10.4049/JIMMUNOL.1202531
P407
P50
P577
2013-02-01T00:00:00Z