MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration.
about
Adenosine Triphosphate (ATP) Inhibits Voltage-Sensitive Potassium Currents in Isolated Hensen's Cells and Nifedipine Protects Against Noise-Induced Hearing Loss in Guinea Pigs.The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability.Mitochondrial protein Fus1/Tusc2 in premature aging and age-related pathologies: critical roles of calcium and energy homeostasisMICU1 drives glycolysis and chemoresistance in ovarian cancer.The mitochondrial Ca2+ uniporter: regulation by auxiliary subunits and signal transduction pathways.MICU1 may be a promising intervention target for gut-derived sepsis induced by intra-abdominal hypertension.MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload.Inhibiting the Mitochondrial Calcium Uniporter during Development Impairs Memory in Adult Drosophila.The In Vivo Biology of the Mitochondrial Calcium Uniporter.Calcium at the Center of Cell Signaling: Interplay between Endoplasmic Reticulum, Mitochondria, and Lysosomes.The Roles of Mitochondrial Cation Channels Under Physiological Conditions and in Cancer.New insights into the role of mitochondrial calcium homeostasis in cell migration.Endoplasmic Reticulum-Mitochondrial Ca2+ Fluxes Underlying Cancer Cell Survival.Intracellular Ca2+ Sensing: Its Role in Calcium Homeostasis and Signaling.Structure, Activity Regulation, and Role of the Mitochondrial Calcium Uniporter in Health and Disease.The Mitochondrial Ca2+ Uniporter: Structure, Function, and Pharmacology.Role of mitochondrial dysfunction and dysregulation of Ca2+ homeostasis in the pathophysiology of insulin resistance and type 2 diabetes.The path from mitochondrial ROS to aging runs through the mitochondrial permeability transition pore.Pathological consequences of MICU1 mutations on mitochondrial calcium signalling and bioenergetics.Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity.Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter.Strategic Positioning and Biased Activity of the Mitochondrial Calcium Uniporter in Cardiac Muscle.Mitochondrial Ca2+ transport in the endothelium: regulation by ions, redox signalling and mechanical forces.Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity.MICU2 Restricts Spatial Crosstalk between InsP3R and MCU Channels by Regulating Threshold and Gain of MICU1-Mediated Inhibition and Activation of MCU.Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.Over Six Decades of Discovery and Characterization of the Architecture at Mitochondria-Associated Membranes (MAMs).Physiological Characterization of a Plant Mitochondrial Calcium Uniporter in Vitro and in Vivo.Pharmacological modulation of mitochondrial calcium homeostasis.High-affinity cooperative Ca2+ binding by MICU1-MICU2 serves as an on-off switch for the uniporter.Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca2+ Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU.The emerging role of immune dysfunction in mitochondrial diseases as a paradigm for understanding immunometabolism.Mitochondrial Calcium Handling in Physiology and Disease.Calcium Signaling in Liver Injury and RegenerationFOXD1-dependent MICU1 expression regulates mitochondrial activity and cell differentiation
P2860
Q28829682-44BDE2DE-0A70-464E-A607-1810CA260B13Q30274561-87356984-84AA-4FE8-8F65-C44552407F1DQ33563545-87DA6F7F-B0AE-481A-A850-BDC051100D03Q33815720-79AC3868-EA7B-41A6-9272-1F6B4A4BECF7Q37139385-FF47FAB0-286C-45D5-9DEF-45BE867E5650Q37444154-5A4DC7AC-BD33-47DE-AE8B-AD5CD333ED74Q37651609-FC9FF8A4-33B4-47B6-A8DF-9F9F9BE8A3AFQ38436297-0A04F4B2-7254-47D8-9C0B-2816C7CD7F87Q38759800-041CD3AA-5EE9-4579-943A-2FDC2B5D0097Q38969543-2E1A7230-00C5-47CF-9267-2E76600B8E61Q39044112-C755CA85-B95B-4212-B22D-29A608258468Q39299633-66B94B62-D584-45D5-87AC-C3E434C78185Q39313968-453AFA6A-9C40-4BFE-A987-5837E3F9D4D9Q39378745-D29FADEF-42A9-4472-AA3D-CEE5D458E708Q39456070-52CA004F-5062-4351-927F-FCD7E69C90EFQ41370113-04B6C0ED-735A-4628-A90D-3F1189FBFA7FQ41591136-943F5520-291A-47B2-B216-434803C8D3CFQ41628840-40CCDED7-BD40-48D3-BEB6-5676A5302CCDQ42279780-E55A34AA-4D3E-4BBE-B8F4-C4A1CB4A5D2CQ42323948-764A1490-3963-4478-A7C9-33E1450B4F57Q42517468-FF5846BC-29BE-44F0-B730-ACB072E64488Q42725800-860B986D-C582-44E6-BA2D-3053A4086EE1Q46241903-40AA9A94-CA69-4D82-B677-D611930D83CDQ46408932-7805137E-1C0B-4473-B4D2-E927FEE33FDDQ47118758-1D33B8E9-6302-4740-9AE3-9018B66B3F94Q47843948-2A417E32-FAE2-4F4C-BE97-EDFB812E6CA8Q47943098-24F5D1F3-A50E-4DDF-8241-B63970FB0411Q48050819-3FBF8352-0F5A-4C08-BF30-D50283D47C55Q48272301-73E5376A-9774-4A53-90A1-35CE7E4941A8Q48276594-CB36F375-F7FE-4993-AF17-98226CAB5E90Q49326217-E28D3DE5-C845-403A-A9F5-E0F2BF69444BQ49835166-D85085EC-16D9-4E36-88E4-214CF9E15F86Q50618470-E67D8CBA-0AA1-4FD1-8836-9F0CD5572C0EQ57115313-0E914AE9-A985-47BF-A6E7-0B65FDDC8E94Q58005048-F2D55174-644A-4C2B-AE0C-DD62C3664E40
P2860
MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
MICU1 regulation of mitochondr ...... vival and tissue regeneration.
@ast
MICU1 regulation of mitochondr ...... vival and tissue regeneration.
@en
type
label
MICU1 regulation of mitochondr ...... vival and tissue regeneration.
@ast
MICU1 regulation of mitochondr ...... vival and tissue regeneration.
@en
prefLabel
MICU1 regulation of mitochondr ...... vival and tissue regeneration.
@ast
MICU1 regulation of mitochondr ...... vival and tissue regeneration.
@en
P2093
P2860
P50
P356
P1476
MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration
@en
P2093
Anil Noronha Antony
Brad Bolon
Cynthia Moffat
Emanuel Rubin
Erin L Seifert
György Csordás
György Hajnóczky
Jason Correnti
P2860
P2888
P356
10.1038/NCOMMS10955
P407
P577
2016-03-09T00:00:00Z