A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
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The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor designEffects of Glycosylation on the Enzymatic Activity and Mechanisms of ProteasesBacterial Proteasomes: Mechanistic and Functional InsightsTowards Selective Mycobacterial ClpP1P2 Inhibitors with Reduced Activity against the Human Proteasome.Structural insights into the functional cycle of the ATPase module of the 26S proteasome.Proteasome dynamics between proliferation and quiescence stages of Saccharomyces cerevisiae.Bacterial proteases, untapped antimicrobial drug targets.A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit β5i.Proteasome Structure and Assembly.Structural characterization of the bacterial proteasome homolog BPH reveals a tetradecameric double-ring complex with unique inner cavity properties.Molecular Mechanisms of the Cardiotoxicity of the Proteasomal-Targeted Drugs Bortezomib and Carfilzomib.Tunable Probes with Direct Fluorescence Signals for the Constitutive and Immunoproteasome.Structural Elucidation of a Nonpeptidic Inhibitor Specific for the Human Immunoproteasome.Defective immuno- and thymoproteasome assembly causes severe immunodeficiency.Inhibition of the proteasome activity by graphene oxide contributes to its cytotoxicity.
P2860
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P2860
A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
@ast
A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
@en
type
label
A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
@ast
A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
@en
prefLabel
A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
@ast
A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
@en
P2093
P2860
P356
P1476
A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome
@en
P2093
Cassandra S Arendt
Eva M Huber
Michael Groll
Wolfgang Heinemeyer
P2860
P2888
P356
10.1038/NCOMMS10900
P407
P577
2016-03-11T00:00:00Z