Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists.
about
The GABAβ receptor as a target for antidepressant drug actionA cyclic peptide mimicking the third intracellular loop of the V2 vasopressin receptor inhibits signaling through its interaction with receptor dimer and G proteinBlockade of GABA(B) receptors completely reverses age-related learning impairment.Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior.2-Aminoethyl methylphosphonate, a potent and rapidly acting antagonist of GABA(A)-ρ1 receptors.Human brain somatostatin release from isolated cortical nerve endings and its modulation through GABAB receptors.Diametric stereocontrol in dynamic catalytic reduction of racemic acyl phosphonates: divergence from α-keto ester congenersNovel, potent, and selective GABAC antagonists inhibit myopia development and facilitate learning and memory.Medicinal chemistry of ρ GABAC receptors.Antidepressant-like activity of CGP 36742 and CGP 51176, selective GABAB receptor antagonists, in rodents.General synthesis of P-stereogenic compounds: the menthyl phosphinate approach.Beta and gamma range EEG power-spectrum correlation with spiking discharges in DBA/2J mice absence model: role of GABA receptors.An historical perspective on GABAergic drugs.Molecular targets for the rational design of antiepileptic drugs and related neuroprotective agents.Comparison of antagonist potencies at pre- and post-synaptic GABA(B) receptors at inhibitory synapses in the CA1 region of the rat hippocampus.Electrophysiological actions of GABAB agonists and antagonists in rat dorso-lateral septal neurones in vitro.Organocatalytic enantioselective synthesis of both diastereomers of alpha-hydroxyphosphinates.Differential expression of metabotropic glutamate and GABA receptors at neocortical glutamatergic and GABAergic axon terminals.Stereogenic phosphorus-induced diastereoselective formation of chiral carbon during nucleophilic addition of chiral H-P species to aldehydes or ketones.Different subtypes of GABAB receptors are present at pre- and postsynaptic sites within the rat dorsolateral septal nucleus.Agonists of the γ-aminobutyric acid type B (GABAB) receptor derived from β-hydroxy and β-amino difluoromethyl ketones.Rapid and Efficient Synthesis of Unsymmetrical Phosphinic Acids R′P(O)OHR″
P2860
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P2860
Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists.
@ast
Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists.
@en
type
label
Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists.
@ast
Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists.
@en
prefLabel
Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists.
@ast
Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists.
@en
P2093
P356
P1476
Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists.
@en
P2093
Baumann PA
Bernasconi R
von Sprecher G
P304
P356
10.1021/JM00017A016
P407
P577
1995-08-01T00:00:00Z