Targeting Nonsquamous Nonsmall Cell Lung Cancer via the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-d]Pyrimidine Thienoyl Antifolates.
about
Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide BiosyFunctional and mechanistic roles of the human proton-coupled folate transporter transmembrane domain 6-7 linker.Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-d]pyrimidine Antifolates.Harnessing Solute Carrier Transporters for Precision Oncology.The promise and challenges of exploiting the proton-coupled folate transporter for selective therapeutic targeting of cancer.Development and validation of chemical features-based proton-coupled folate transporter/activity and reduced folate carrier/activity models (pharmacophores).Fluorine-Substituted Pyrrolo[2,3- d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis.
P2860
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P2860
Targeting Nonsquamous Nonsmall Cell Lung Cancer via the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-d]Pyrimidine Thienoyl Antifolates.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Targeting Nonsquamous Nonsmall ...... rimidine Thienoyl Antifolates.
@ast
Targeting Nonsquamous Nonsmall ...... rimidine Thienoyl Antifolates.
@en
type
label
Targeting Nonsquamous Nonsmall ...... rimidine Thienoyl Antifolates.
@ast
Targeting Nonsquamous Nonsmall ...... rimidine Thienoyl Antifolates.
@en
prefLabel
Targeting Nonsquamous Nonsmall ...... rimidine Thienoyl Antifolates.
@ast
Targeting Nonsquamous Nonsmall ...... rimidine Thienoyl Antifolates.
@en
P2093
P2860
P356
P1476
Targeting Nonsquamous Nonsmall ...... rimidine Thienoyl Antifolates.
@en
P2093
Aleem Gangjee
Jenny Huang
Juiwanna Kushner
Kathryn White
Larry H Matherly
Lisa Polin
Manohar Ratnam
Mike R Wilson
Zhanjun Hou
P2860
P304
P356
10.1124/MOL.115.102798
P577
2016-02-02T00:00:00Z