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Altered cerebral protein synthesis in fragile X syndrome: studies in human subjects and knockout mice

Altered cerebral protein synthesis in fragile X syndrome: studies in human subjects and knockout mice

http://www.wikidata.org/entity/Q36745099

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Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome The PI3K signaling pathway as a pharmacological target in Autism related disorders and Schizophrenia.Genes, circuits, and precision therapies for autism and related neurodevelopmental disorders Dysregulation and restoration of translational homeostasis in fragile X syndrome Delta rhythmicity is a reliable EEG biomarker in Angelman syndrome: a parallel mouse and human analysis.Identification of fragile X syndrome specific molecular markers in human fibroblasts: a useful model to test the efficacy of therapeutic drugs.The Fragile X proteins Fmrp and Fxr2p cooperate to regulate glucose metabolism in mice.Elevated CaMKIIα and Hyperphosphorylation of Homer Mediate Circuit Dysfunction in a Fragile X Syndrome Mouse Model.PET radiopharmaceuticals for probing enzymes in the brain Selective Deletion of Astroglial FMRP Dysregulates Glutamate Transporter GLT1 and Contributes to Fragile X Syndrome Phenotypes In Vivo.Endocannabinoid-mediated improvement on a test of aversive memory in a mouse model of fragile X syndrome.Protein synthesis levels are increased in a subset of individuals with Fragile X syndrome.Effects of shortened scanning intervals on calculated regional rates of cerebral protein synthesis determined with the L-[1-11C]leucine PET method.The Intracellular Cleavage Product of the NG2 Proteoglycan Modulates Translation and Cell-Cycle Kinetics via Effects on mTORC1/FMRP Signaling

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Altered cerebral protein synthesis in fragile X syndrome: studies in human subjects and knockout mice

http://www.wikidata.org/entity/Q36745099

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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name

Altered cerebral protein synth ...... man subjects and knockout mice

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Altered cerebral protein synth ...... man subjects and knockout mice

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Altered cerebral protein synth ...... man subjects and knockout mice

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Altered cerebral protein synth ...... man subjects and knockout mice

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Journal of Cerebral Blood Flow & Metabolism

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Altered cerebral protein synth ...... man subjects and knockout mice

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P2093

Alan J Zametkin

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Carolyn Beebe Smith

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Kathleen C Schmidt

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Lisa M Horowitz

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Mei Qin

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Shrinivas Bishu

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Thomas V Burlin

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Tianjiang Huang

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Zengyan Xia

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P2860

FMR1 protein: conserved RNP family domains and selective RNA binding

High-affinity blockade of voltage-operated skeletal muscle and neuronal sodium channels by halogenated propofol analogues

Evidence that fragile X mental retardation protein is a negative regulator of translation

The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes

The fragile X mental retardation protein inhibits translation via interacting with mRNA

Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function

Voxel-based estimation of kinetic model parameters of the L-[1-(11)C]leucine PET method for determination of regional rates of cerebral protein synthesis: validation and comparison with region-of-interest-based methods

Measurement of local cerebral protein synthesis in vivo: influence of recycling of amino acids derived from protein degradation.

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499-507

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scholarly article

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10.1038/JCBFM.2012.205

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4

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33

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Zenaide Quezado

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2013-01-09T00:00:00Z

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23299245

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human subject research

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3618394

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