Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation.
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The mechanical regulation of integrin-cadherin crosstalk organizes cells, signaling and forcesThe adaptor protein Shc integrates growth factor and ECM signaling during postnatal angiogenesis.Integrins and cadherins join forces to form adhesive networks.Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathwayCoronary artery remodeling in a model of left ventricular pressure overload is influenced by platelets and inflammatory cells.Hemodynamic shear stress and the endothelium in cardiovascular pathophysiologyAdaptor protein Shc acts as an immune-regulator for the LPS-stimulated maturation of bone marrow-derived dendritic cellsEffects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectivesPlatelet-endothelial cell adhesion molecule-1 regulates endothelial NO synthase activity and localization through signal transducers and activators of transcription 3-dependent NOSTRIN expression.Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex.Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism.A novel pathway spatiotemporally activates Rac1 and redox signaling in response to fluid shear stressPECAM-1 is necessary for flow-induced vascular remodelingEndothelial Shc regulates arteriogenesis through dual control of arterial specification and inflammation via the notch and nuclear factor-κ-light-chain-enhancer of activated B-cell pathways.Lessons from the endothelial junctional mechanosensory complex.Molecular biology of atherosclerosis.Shear stress-initiated signaling and its regulation of endothelial function.Endothelial mechanosensors: the gatekeepers of vascular homeostasis and adaptation under mechanical stress.Thioredoxin-interacting protein is a biomechanical regulator of Src activity: key role in endothelial cell stress fiber formation.Effects of shear stress on endothelial cells: go with the flow.Endothelial Mechanosignaling: Does One Sensor Fit All?Blood Brothers: Hemodynamics and Cell-Matrix Interactions in Endothelial Function.Shc and the mechanotransduction of cellular anchorage and metastasis.High-cell density-induced VCAM1 expression inhibits the migratory ability of mesenchymal stem cells.Mechanical signals activate vascular endothelial growth factor receptor-2 to upregulate endothelial cell proliferation during inflammation.p66Shc couples mechanical signals to RhoA through FAK-dependent recruitment of p115-RhoGEF and GEF-H1.Activation of aortic endothelial cells by oxidized phospholipids: a phosphoproteomic analysis.Spatial signaling networks converge at the adaptor protein Shc.ATHEROSCLEROSIS NEEDS SHC.The Role of Midkine in Arteriogenesis, Involving Mechanosensing, Endothelial Cell Proliferation, and Vasodilation
P2860
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P2860
Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Shc coordinates signals from i ...... ate flow-induced inflammation.
@en
type
label
Shc coordinates signals from i ...... ate flow-induced inflammation.
@en
prefLabel
Shc coordinates signals from i ...... ate flow-induced inflammation.
@en
P2093
P2860
P356
P1476
Shc coordinates signals from i ...... ate flow-induced inflammation.
@en
P2093
Daniel Timothy Sweet
Ellie Tzima
Mohamad Irani-Tehrani
Nobuyo Maeda
Yunhao Liu
P2860
P304
P356
10.1083/JCB.200709176
P407
P577
2008-07-07T00:00:00Z