Genetic dissection of the biosynthetic route to gentamicin A2 by heterologous expression of its minimal gene set.
about
Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.Delineating the biosynthesis of gentamicin x2, the common precursor of the gentamicin C antibiotic complex.Development of a Streptomyces venezuelae-based combinatorial biosynthetic system for the production of glycosylated derivatives of doxorubicin and its biosynthetic intermediates.Radical SAM enzymes in the biosynthesis of sugar-containing natural products.Assembly of a novel biosynthetic pathway for gentamicin B production in Micromonospora echinospora.C3'-Deoxygenation of Paromamine Catalyzed by a Radical S-Adenosylmethionine Enzyme: Characterization of the Enzyme AprD4 and Its Reductase Partner AprD3.Progress in aminocyclitol biosynthesis.GenK-catalyzed C-6' methylation in the biosynthesis of gentamicin: isolation and characterization of a cobalamin-dependent radical SAM enzyme.Biosynthetic genes for aminoglycoside antibiotics.2-Deoxystreptamine-containing aminoglycoside antibiotics: recent advances in the characterization and manipulation of their biosynthetic pathways.Achievements and impacts of glycosylation reactions involved in natural product biosynthesis in prokaryotes.Developing Streptomyces venezuelae as a cell factory for the production of small molecules used in drug discovery.Aminoglycoside Antibiotics: New Insights into the Biosynthetic Machinery of Old Drugs.Parallel pathways in the biosynthesis of aminoglycoside antibiotics.An insight into the "-omics" based engineering of streptomycetes for secondary metabolite overproduction.Specificity and promiscuity at the branch point in gentamicin biosynthesis.Characterization and engineering of the ethylmalonyl-CoA pathway towards the improved heterologous production of polyketides in Streptomyces venezuelae.Consolidated presentation of the joint Scientific Opinion of the GMO and BIOHAZ Panels on the “Use of Antibiotic Resistance Genes as Marker Genes in Genetically Modified Plants” and the Scientific Opinion of the GMO Panel on “Consequences of the O...Methyltransferases of gentamicin biosynthesis.Istamycin aminoglycosides profiling and their characterization in Streptomyces tenjimariensis ATCC 31603 culture using high-performance liquid chromatography with tandem mass spectrometry.Characterization of fortimicin aminoglycoside profiles produced from Micromonospora olivasterospora DSM 43868 by high-performance liquid chromatography-electrospray ionization-ion trap-mass spectrometry.Construction of kanamycin B overproducing strain by genetic engineering of Streptomyces tenebrarius.Genetic engineering combined with random mutagenesis to enhance G418 production in Micromonospora echinospora.
P2860
Q34222579-38116741-7FCE-4053-A7E1-2F0B944DA77DQ35122210-67876E61-6718-434F-BEA8-CE7AE9828FFCQ35138927-4927551B-542E-4EA0-AF9A-46611594ED19Q36223612-75D3E2F3-DCA5-4F94-873A-459583CFD50DQ36428324-632B09D2-60AD-4946-AEFA-30D0AC839D10Q37092428-88172902-81C1-4A41-8D16-EA035CB58F52Q37179506-05CB33CA-018F-40E9-8290-E585ACF98AC1Q37228577-D21F8072-4B33-4186-A149-3403C572FE6BQ37567445-F6DFEE72-D187-4CEA-8DD5-49A502875F78Q38062339-6969D9E7-D218-4EFD-A3B0-E0156C1D018EQ38110187-D6959ED6-AAFB-4B47-B1A5-326CEB201C83Q38554510-AA5BA2F1-45D6-4706-9B8F-B9C00BF3CC08Q38604106-746F9D97-FD1F-4777-8622-179B7370C1B3Q38670416-56E58A6B-77CC-4FFA-BE70-BE1CA35AF8A2Q42181821-D6B915C4-280A-4F42-B026-99A133730536Q42601491-33753C73-0DFB-434B-BBE3-FDD77D6D733CQ44152357-382CB0AD-2B25-4946-8C29-5142FB2CD278Q47146838-183A9C81-982A-4B55-87F1-1635D722AD24Q47803598-72D1A8DE-1076-49D5-A3DA-E0982D5981BBQ51124712-0E392357-ECE1-470B-861F-9BAF7224CAEAQ51566976-E0BD29C5-E8DF-4854-B81A-04059C291FBBQ52604211-55D6C3B2-7079-4B0F-B931-EFA4F21FBDFEQ53500312-BA8EC7E2-C3FF-4269-A88E-030A1A52AE14
P2860
Genetic dissection of the biosynthetic route to gentamicin A2 by heterologous expression of its minimal gene set.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Genetic dissection of the bios ...... ssion of its minimal gene set.
@en
type
label
Genetic dissection of the bios ...... ssion of its minimal gene set.
@en
prefLabel
Genetic dissection of the bios ...... ssion of its minimal gene set.
@en
P2093
P2860
P356
P1476
Genetic dissection of the bios ...... ssion of its minimal gene set.
@en
P2093
Jae Kyung Sohng
Jay Sung Joong Hong
Je Won Park
Niranjan Parajuli
Si-Kyu Lim
Sung Ryeol Park
Won Seok Jung
Yeo Joon Yoon
P2860
P304
P356
10.1073/PNAS.0803164105
P407
P577
2008-06-12T00:00:00Z