Hypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress.
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Mechanisms of Action Involved in Ozone Therapy: Is healing induced via a mild oxidative stress?Selective inhibition of hypoxia-inducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathwaysThermal unfolding pathway of PHD2 catalytic domain in three different PHD2 species: computational approachesDifferential effects of collagen prolyl 3-hydroxylation on skeletal tissuesMolecular mechanisms of action and therapeutic uses of pharmacological inhibitors of HIF-prolyl 4-hydroxylases for treatment of ischemic diseasesSmall changes huge impact: the role of protein posttranslational modifications in cellular homeostasis and diseaseChick embryo partial ischemia model: a new approach to study ischemia ex vivoRapid degradation of hypoxia-inducible factor-1alpha by KRH102053, a new activator of prolyl hydroxylase 2.Small molecule signaling agents: the integrated chemistry and biochemistry of nitrogen oxides, oxides of carbon, dioxygen, hydrogen sulfide, and their derived speciesRas oncogene and Hypoxia-inducible factor-1 alpha (hif-1α) expression in the Amazon fish Colossoma macropomum (Cuvier, 1818) exposed to benzo[a]pyrene.Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injuryRegulation of cellular levels of Sprouty2 protein by prolyl hydroxylase domain and von Hippel-Lindau proteinsAcute Heat Stress and Reduced Nutrient Intake Alter Intestinal Proteomic Profile and Gene Expression in PigsHypoxia-inducible factor 1 protects hypoxic astrocytes against glutamate toxicity.Intracellular Iron Chelation Modulates the Macrophage Iron Phenotype with Consequences on Tumor Progression.Intravenous high mobility group box 1 upregulates the expression of HIF-1α in the myocardium via a protein kinase B-dependent pathway in rats following acute myocardial ischemia.The chemistry of cell signaling by reactive oxygen and nitrogen species and 4-hydroxynonenal.Prolyl 4-hydroxylase activity-responsive transcription factors: from hydroxylation to gene expression and neuroprotection.Metabolic profiling of PPARalpha-/- mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementationIs cancer a severe delayed hypersensitivity reaction and histamine a blueprint?Prolyl 4-hydroxylases, key enzymes in the synthesis of collagens and regulation of the response to hypoxia, and their roles as treatment targets.Neuroprotective molecular mechanisms of (-)-epigallocatechin-3-gallate: a reflective outcome of its antioxidant, iron chelating and neuritogenic properties.Two distinct roles for EGL-9 in the regulation of HIF-1-mediated gene expression in Caenorhabditis elegans.Hemodynamic response to treatment of iron deficiency anemia in pulmonary arterial hypertension: longitudinal insights from an implantable hemodynamic monitor.Hypoxia inducible factor 1 as a therapeutic target in ischemic stroke.Promise of neurorestoration and mitochondrial biogenesis in Parkinson's disease with multi target drugs: an alternative to stem cell therapy.Antioxidant and protective mechanisms against hypoxia and hypoglycaemia in cortical neurons in vitroProlyl hydroxylase inhibitors act as agents to enhance the efficiency of cell therapy.Benzimidazole-2-pyrazole HIF Prolyl 4-Hydroxylase Inhibitors as Oral Erythropoietin Secretagogues.Specific inhibition of hypoxia inducible factor 1 exaggerates cell injury induced by in vitro ischemia through deteriorating cellular redox environmentAdaptation to moderate hypoxia protects cortical neurons against ischemia-reperfusion injury and excitotoxicity independently of HIF-1α.TCA cycle rewiring fosters metabolic adaptation to oxygen restriction in skeletal muscle from rodents and humans.Inhibition of HIF prolyl-4-hydroxylases by FG-4497 reduces brain tissue injury and edema formation during ischemic stroke.Inhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis.Synthesis of a FTO inhibitor with anticonvulsant activity.Life after SAINT.Pre-treatment with the synthetic antioxidant T-butyl bisphenol protects cerebral tissues from experimental ischemia reperfusion injury.Angiotensin II differentially regulates Morg1 expression in kidney cells.Effects of antidepressant drug exposure on gene expression in the developing cerebral cortex.Cell-specific and hypoxia-dependent regulation of human HIF-3α: inhibition of the expression of HIF target genes in vascular cells.
P2860
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P2860
Hypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Hypoxia inducible factor proly ...... mpromise and oxidative stress.
@en
type
label
Hypoxia inducible factor proly ...... mpromise and oxidative stress.
@en
prefLabel
Hypoxia inducible factor proly ...... mpromise and oxidative stress.
@en
P2093
P2860
P1476
Hypoxia inducible factor proly ...... mpromise and oxidative stress.
@en
P2093
Ambreena Siddiq
Leila R Aminova
Rajiv R Ratan
P2860
P2888
P304
P356
10.1007/S11064-006-9268-7
P577
2007-03-07T00:00:00Z