Complement inhibition prevents oncolytic vaccinia virus neutralization in immune humans and cynomolgus macaques - Test2 - elhamkhani - TriplyDB

Complement inhibition prevents oncolytic vaccinia virus neutralization in immune humans and cynomolgus macaques

Complement inhibition prevents oncolytic vaccinia virus neutralization in immune humans and cynomolgus macaques

http://www.wikidata.org/entity/Q36756690

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Viruses as nanomedicine for cancer Polymeric Cups for Cavitation-mediated Delivery of Oncolytic Vaccinia Virus.Preclinical Safety Studies of Enadenotucirev, a Chimeric Group B Human-Specific Oncolytic Adenovirus Oncolytic Immunotherapy: Conceptual Evolution, Current Strategies, and Future Perspectives Successive site translocating inoculation potentiates DNA/recombinant vaccinia vaccination Murine Tumor Models for Oncolytic Rhabdo-Virotherapy.Phase 1 Study of Intravenous Oncolytic Poxvirus (vvDD) in Patients With Advanced Solid Cancers.Complement inhibition enables tumor delivery of LCMV glycoprotein pseudotyped viruses in the presence of antiviral antibodies.Talimogene Laherparepvec (T-VEC) and Other Oncolytic Viruses for the Treatment of Melanoma.Advances in systemic delivery of anti-cancer agents for the treatment of metastatic cancer.Oncolytic viruses-immunotherapeutics on the rise.Maraba virus-vectored cancer vaccines represent a safe and novel therapeutic option for cats.Prospects for combined use of oncolytic viruses and CAR T-cells.Complement Inhibition: A Novel Form of Immunotherapy for Colon Cancer.Recombinant Poxvirus and the Tumor Microenvironment: Oncolysis, Immune Regulation and Immunization.Potential of oncolytic viruses in the treatment of multiple myeloma.From Benchtop to Bedside: A Review of Oncolytic Virotherapy.Influence of Pre-existing Anti-capsid Neutralizing and Binding Antibodies on AAV Vector Transduction.Taking a Stab at Cancer; Oncolytic Virus-Mediated Anti-Cancer Vaccination Strategies.Oncolytic Viruses as Therapeutic Tools for Pediatric Brain Tumors White paper on microbial anti-cancer therapy and prevention

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P2860

Complement inhibition prevents oncolytic vaccinia virus neutralization in immune humans and cynomolgus macaques

http://www.wikidata.org/entity/Q36756690

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2015 nî lūn-bûn

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2015年论文

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2015年论文

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2015年论文

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Molecular Therapy

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Alyssa Goldstein

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C Scott Findlay

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Caroline J Breitbach

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Chantal G Lemay

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Christiano Tanese de Souza

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David Hanwell

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David Kirn

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Harold Atkins

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J Andrea McCart

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Joshua M Thurman

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P2860

New viruses for cancer therapy: meeting clinical needs

Compstatin: a complement inhibitor on its way to clinical application

Potent Neutralization of Vaccinia Virus by Divergent Murine Antibodies Targeting a Common Site of Vulnerability in L1 Protein

Complement: a key system for immune surveillance and homeostasis

Complement is activated by IgG hexamers assembled at the cell surface.

Fluorochrome-linked immunoassay for functional analysis of the mannose binding lectin complement pathway to the level of C3 cleavage.

Enhanced tumor uptake and penetration of virotherapy using polymer stealthing and focused ultrasound

Identification of human mannose binding lectin (MBL) recognition sites for novel inhibitory antibodies.

Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trial.

Inhibitors of C5 complement enhance vaccinia virus oncolysis.

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1066-1076

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10.1038/MT.2015.49

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6

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23

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John D. Lambris

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2015-03-25T00:00:00Z

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25807289

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oncolytic virus

molecular medicine

molecular biology

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4817751

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