A conspicuous connection: structure defines function for the phosphatidylinositol-phosphate kinase family.
about
The poly A polymerase Star-PAP controls 3'-end cleavage by promoting CPSF interaction and specificity toward the pre-mRNACKIalpha is associated with and phosphorylates star-PAP and is also required for expression of select star-PAP target messenger RNAsIQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration.Phosphoinositide signaling regulates the exocyst complex and polarized integrin trafficking in directionally migrating cellsPlatelet lipidomics: modern day perspective on lipid discovery and characterization in plateletsRegulation of platelet plug formation by phosphoinositide metabolismAssembly of the PtdIns 4-kinase Stt4 complex at the plasma membrane requires Ypp1 and Efr3.PIP kinases define PI4,5P₂signaling specificity by association with effectorsPhosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brainPlatelets lacking PIP5KIγ have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesionLAPTM4B is a PtdIns(4,5)P2 effector that regulates EGFR signaling, lysosomal sorting, and degradation.Positive selection for the male functionality of a co-retroposed gene in the hominoidsIsoform 5 of PIPKIγ regulates the endosomal trafficking and degradation of E-cadherin.Nuclear phosphoinositides: a signaling enigma wrapped in a compartmental conundrum.Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system.The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamicsPhosphatidylinositol 4,5-bisphosphate: targeted production and signalingEZH2 regulates neuronal differentiation of mesenchymal stem cells through PIP5K1C-dependent calcium signalingPhosphoinositide phosphatases and disease.IQGAPs choreograph cellular signaling from the membrane to the nucleusStar-PAP control of BIK expression and apoptosis is regulated by nuclear PIPKIα and PKCδ signaling.IRBIT Interacts with the Catalytic Core of Phosphatidylinositol Phosphate Kinase Type Iα and IIα through Conserved Catalytic Aspartate Residues.A novel gene expression pathway regulated by nuclear phosphoinositidesPhosphatidylinositol Phosphate 5-Kinase Iγ and Phosphoinositide 3-Kinase/Akt Signaling Couple to Promote Oncogenic Growth.Resolution of structure of PIP5K1A reveals molecular mechanism for its regulation by dimerization and dishevelled.Type I gamma phosphatidylinositol phosphate kinase is required for EGF-stimulated directional cell migrationPhosphatidylinositol-4-phosphate 5-kinase isoforms exhibit acyl chain selectivity for both substrate and lipid activatorThe novel poly(A) polymerase Star-PAP is a signal-regulated switch at the 3'-end of mRNAs.Endosomal type Iγ PIP 5-kinase controls EGF receptor lysosomal sortingOut, in and back again: PtdIns(4,5)P(2) regulates cadherin trafficking in epithelial morphogenesis.Mechanism of substrate specificity of phosphatidylinositol phosphate kinases.Genome-wide analysis of the phosphoinositide kinome from two ciliates reveals novel evolutionary links for phosphoinositide kinases in eukaryotic cellsPhosphatidylinositol phosphate 5-kinase Iγi2 in association with Src controls anchorage-independent growth of tumor cells.The Hidden Conundrum of Phosphoinositide Signaling in CancerTwo novel phosphatidylinositol-4-phosphate 5-kinase type Igamma splice variants expressed in human cells display distinctive cellular targeting.A reciprocal interdependence between Nck and PI(4,5)P(2) promotes localized N-WASp-mediated actin polymerization in living cells.Nuclear phosphoinositides and their roles in cell biology and disease.Viral infection: Moving through complex and dynamic cell-membrane structures.IQGAP1 is a phosphoinositide effector and kinase scaffoldType I γ Phosphatidylinositol Phosphate 5-Kinase i5 Controls the Ubiquitination and Degradation of the Tumor Suppressor Mitogen-inducible Gene 6
P2860
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P2860
A conspicuous connection: structure defines function for the phosphatidylinositol-phosphate kinase family.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
A conspicuous connection: stru ...... sitol-phosphate kinase family.
@ast
A conspicuous connection: stru ...... sitol-phosphate kinase family.
@en
type
label
A conspicuous connection: stru ...... sitol-phosphate kinase family.
@ast
A conspicuous connection: stru ...... sitol-phosphate kinase family.
@en
prefLabel
A conspicuous connection: stru ...... sitol-phosphate kinase family.
@ast
A conspicuous connection: stru ...... sitol-phosphate kinase family.
@en
P2093
P2860
P1476
A conspicuous connection: stru ...... ositol-phosphate kinase family
@en
P2093
David L Mellman
Jessica N Heck
Matthew P Wagoner
P2860
P356
10.1080/10409230601162752
P577
2007-01-01T00:00:00Z