Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver.
about
Activation of ERK and NF-κB during HARE-Mediated Heparin Uptake Require Only One of the Four Endocytic Motifs.VEGF-sdf1 recruitment of CXCR7+ bone marrow progenitors of liver sinusoidal endothelial cells promotes rat liver regeneration.Antisense Oligonucleotides: Treatment Strategies and Cellular Internalization.Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor.Fluorinated Nucleotide Modifications Modulate Allele Selectivity of SNP-Targeting Antisense Oligonucleotides.Managing the sequence-specificity of antisense oligonucleotides in drug discovery.Intra-endosomal trafficking mediated by lysobisphosphatidic acid contributes to intracellular release of phosphorothioate-modified antisense oligonucleotidesAsialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides into liver hepatocytes.Directing Nanoparticle Biodistribution through Evasion and Exploitation of Stab2-Dependent Nanoparticle Uptake.Oligonucleotide therapies for disorders of the nervous system.Endosomal Escape of ASOs Internalized by Stabilin Receptors Is Regulated by Rab5C and EEA1 During Endosomal Maturation.Receptor-Mediated Uptake of Phosphorothioate Antisense Oligonucleotides in Different Cell Types of the Liver.Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology.Cellular uptake mediated by epidermal growth factor receptor facilitates the intracellular activity of phosphorothioate-modified antisense oligonucleotides.Structural Determinants for the Interactions of Chemically Modified Nucleic Acids with the Stabilin-2 Clearance Receptor.Targeted delivery of antisense oligonucleotides to pancreatic β-cellsCOPII vesicles can affect the activity of antisense oligonucleotides by facilitating the release of oligonucleotides from endocytic pathways
P2860
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P2860
Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Stabilin-1 and Stabilin-2 are ...... cleotides (ASOs) in the liver.
@ast
Stabilin-1 and Stabilin-2 are ...... cleotides (ASOs) in the liver.
@en
type
label
Stabilin-1 and Stabilin-2 are ...... cleotides (ASOs) in the liver.
@ast
Stabilin-1 and Stabilin-2 are ...... cleotides (ASOs) in the liver.
@en
prefLabel
Stabilin-1 and Stabilin-2 are ...... cleotides (ASOs) in the liver.
@ast
Stabilin-1 and Stabilin-2 are ...... cleotides (ASOs) in the liver.
@en
P2093
P2860
P356
P1476
Stabilin-1 and Stabilin-2 are ...... cleotides (ASOs) in the liver.
@en
P2093
Aaron J Donner
Andrew W Egger
Brianna M Kellar
Colton M Miller
Edward N Harris
Emma E Blank
Michael E Østergaard
Punit P Seth
P2860
P304
P356
10.1093/NAR/GKW112
P407
P577
2016-02-22T00:00:00Z