Interactions of mutant p53 with DNA: guilt by association.
about
Estrogen receptor acting in cis enhances WT and mutant p53 transactivation at canonical and noncanonical p53 target sequences.Combined PTEN Mutation and Protein Expression Associate with Overall and Disease-Free Survival of Glioblastoma Patients.Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cellsPreferential binding of hot spot mutant p53 proteins to supercoiled DNA in vitro and in cells.Forced expression of heat shock protein 27 (Hsp27) reverses P-glycoprotein (ABCB1)-mediated drug efflux and MDR1 gene expression in Adriamycin-resistant human breast cancer cellsMutant p53: one name, many proteins.Reduction of p53 by knockdown of the UGT1 locus in colon epithelial cells causes an increase in tumorigenesis.Phase 2 randomized study of p53 antisense oligonucleotide (cenersen) plus idarubicin with or without cytarabine in refractory and relapsed acute myeloid leukemia.p53 and regulation of bioactive sphingolipids.Anti-apoptotic NF-κB and "gain of function" mutp53 in concert act pro-apoptotic in response to UVB+IL-1 via enhanced TNF productionTranscriptional Regulation by Wild-Type and Cancer-Related Mutant Forms of p53.Mutants TP53 p.R273H and p.R273C but not p.R273G enhance cancer cell malignancy.Mutant p53 is a transcriptional co-factor that binds to G-rich regulatory regions of active genes and generates transcriptional plasticity.Control of Nucleotide Metabolism Enables Mutant p53's Oncogenic Gain-of-Function Activity.From mutational inactivation to aberrant gain-of-function: Unraveling the structural basis of mutant p53 oncogenic transition.Proteomic identification of ERP29 as a key chemoresistant factor activated by the aggregating p53 mutant Arg282Trp.
P2860
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P2860
Interactions of mutant p53 with DNA: guilt by association.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Interactions of mutant p53 with DNA: guilt by association.
@ast
Interactions of mutant p53 with DNA: guilt by association.
@en
type
label
Interactions of mutant p53 with DNA: guilt by association.
@ast
Interactions of mutant p53 with DNA: guilt by association.
@en
prefLabel
Interactions of mutant p53 with DNA: guilt by association.
@ast
Interactions of mutant p53 with DNA: guilt by association.
@en
P2860
P356
P1433
P1476
Interactions of mutant p53 with DNA: guilt by association.
@en
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210312
P407
P577
2007-04-01T00:00:00Z