Phosphorylation of p53 in normal and simian virus 40-transformed NIH 3T3 cells
about
Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1)Dephosphorylation of simian virus 40 large-T antigen and p53 protein by protein phosphatase 2A: inhibition by small-t antigenp53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent mannerp53-independent endoplasmic reticulum stress-mediated cytotoxicity of a Newcastle disease virus strain in tumor cell linesSmall changes huge impact: the role of protein posttranslational modifications in cellular homeostasis and diseaseHuman DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2Posttranslational modification of p53: cooperative integrators of functionWild-type, but not mutant, human p53 proteins inhibit the replication activities of simian virus 40 large tumor antigen.The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II.Towards inferring time dimensionality in protein-protein interaction networks by integrating structures: the p53 example.The transforming and suppressor functions of p53 alleles: effects of mutations that disrupt phosphorylation, oligomerization and nuclear translocation.p53 functions as a cell cycle control protein in osteosarcomasSerine 312 phosphorylation is dispensable for wild-type p53 functions in vivo.Is the inhibition of protein phosphatase 1 and 2A activities a general mechanism of tumor promotion in human cancer development?Nuclear protein phosphorylation and growth control.Protein phosphatases and DNA tumor viruses: transformation through the back door?Species-specific phosphorylation of mouse and rat p53 in simian virus 40-transformed cells.Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen.Simian virus 40 can overcome the antiproliferative effect of wild-type p53 in the absence of stable large T antigen-p53 binding.Mutation of the serine 312 phosphorylation site does not alter the ability of mouse p53 to inhibit simian virus 40 DNA replication in vivo.Expression and complex formation of simian virus 40 large T antigen and mouse p53 in insect cells.Phosphorylation sites in the amino-terminal region of mouse p53.Analysis of genomic instability in Li-Fraumeni fibroblasts with germline p53 mutations.Phosphorylation studies on rat p53 using the baculovirus expression system. Manipulation of the phosphorylation state with okadaic acid and influence on DNA binding.The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro.Altered phosphorylation of free and bound forms of monkey p53 and simian virus 40 large T antigen during lytic infection.Simian virus 40 large T antigen induces or activates a protein kinase which phosphorylates the transformation-associated protein p53.Oligomerization of oncoprotein p53.Mutation of the casein kinase II phosphorylation site abolishes the anti-proliferative activity of p53.The tumor suppressor p53 is bound to RNA by a stable covalent linkage.Human p53 and CDC2Hs genes combine to inhibit the proliferation of Saccharomyces cerevisiae.Human p53 inhibits growth in Schizosaccharomyces pombePhosphopeptide mapping and phosphoamino acid analysis by electrophoresis and chromatography on thin-layer cellulose plates.p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1.p53 is covalently linked to 5.8S rRNA.Evidence for allosteric variants of wild-type p53, a tumour suppressor protein.Mutation of phosphoserine 389 affects p53 function in vivo.Frequent phosphorylation at serine 392 in overexpressed p53 protein due to missense mutation in carcinoma of the urinary tract.
P2860
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P2860
Phosphorylation of p53 in normal and simian virus 40-transformed NIH 3T3 cells
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Phosphorylation of p53 in normal and simian virus 40-transformed NIH 3T3 cells
@en
type
label
Phosphorylation of p53 in normal and simian virus 40-transformed NIH 3T3 cells
@en
prefLabel
Phosphorylation of p53 in normal and simian virus 40-transformed NIH 3T3 cells
@en
P2860
P356
P1476
Phosphorylation of p53 in normal and simian virus 40-transformed NIH 3T3 cells
@en
P2093
P2860
P304
P356
10.1128/MCB.8.1.461
P407
P577
1988-01-01T00:00:00Z