Identification of the amino-acetonitrile derivative monepantel (AAD 1566) as a new anthelmintic drug development candidate.
about
Genome of the human hookworm Necator americanusPotential drug development candidates for human soil-transmitted helminthiasesHaemonchus contortus acetylcholine receptors of the DEG-3 subfamily and their role in sensitivity to monepantelPhylogenomics of ligand-gated ion channels predicts monepantel effectFunctional characterization of a novel family of acetylcholine-gated chloride channels in Schistosoma mansoniRecent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions.Computational cloning of drug target genes of a parasitic nematode, Oesophagostomum dentatum.Genome-wide tissue-specific gene expression, co-expression and regulation of co-expressed genes in adult nematode Ascaris suum.Expression of five acetylcholine receptor subunit genes in Brugia malayi adult wormsWhole-cell patch-clamp recording of nicotinic acetylcholine receptors in adult Brugia malayi muscle.Pharmacological profile of Ascaris suum ACR-16, a new homomeric nicotinic acetylcholine receptor widely distributed in Ascaris tissuesIon channels and receptor as targets for the control of parasitic nematodes.Investigation of acetylcholine receptor diversity in a nematode parasite leads to characterization of tribendimidine- and derquantel-sensitive nAChRs.Managing anthelmintic resistance: is it feasible in New Zealand to delay the emergence of resistance to a new anthelmintic class?The immunobiology of myiasis infections--whatever happened to vaccination?Molecular mechanisms for anthelmintic resistance in strongyle nematode parasites of veterinary importance.A preliminary proteomic characterisation of extracellular vesicles released by the ovine parasitic nematode, Teladorsagia circumcinctaAcetylcholinesterase and Nicotinic Acetylcholine Receptors in Schistosomes and Other Parasitic Helminths.Differences in efficacy of monepantel, derquantel and abamectin against multi-resistant nematodes of sheep.Safety of an amino-acetonitrile derivative (AAD), monepantel, in ewes and their offspring following repeated oral administration.Reproductive safety of an amino-acetonitrile derivative (AAD), monepantel, in rams following repeated oral administration.Safety of an amino-acetonitrile derivative ( AAD ), monepantel, in weaned lambs following repeated oral administration.A large-scale clinical field study to evaluate the efficacy and safety of an oral formulation of the amino-acetonitrile derivative ( AAD ), monepantel , in sheep in New Zealand.The astacin metalloprotease moulting enzyme NAS-36 is required for normal cuticle ecdysis in free-living and parasitic nematodes.Monepantel is a non-competitive antagonist of nicotinic acetylcholine receptors from Ascaris suum and Oesophagostomum dentatum.A BRIEF REVIEW ON THE MODE OF ACTION OF ANTINEMATODAL DRUGS.Efficacy of monepantel, derquantel and abamectin against adult stages of a multi-resistant Haemonchus contortus isolate.Characterization of a multidrug resistant Teladorsagia circumcincta isolate from SpainSuppression of Acetylcholinesterase Affects Parasite Growth and Development
P2860
Q22122067-FD9BE7D6-5378-4FAC-AB96-3B6558C6973EQ27306274-BCD27A41-A421-4116-A160-5EA11AFD49ACQ28475244-07CC4188-10A5-4FEB-8215-9E762645E249Q28475454-72E97E01-8851-40E7-8536-CD1F9A55AA42Q28539660-FF19D833-238D-4BE0-92FC-4265813CC846Q34705912-632E0BCB-9EE9-4338-A43A-96722003BFF8Q34774856-932FD449-69AA-47D9-8EE8-ED500F20778EQ35091848-053251DB-FDFA-484A-82E5-FE790DC5ADF3Q35864932-872BB3B9-F919-4497-AE04-5F4E7109D08CQ37097877-A100484A-1EC6-4B33-9153-4AC910B67837Q37123991-FAC5A41D-8BDA-416D-9B89-98B92BC92F99Q37501925-42CB529D-AFC6-4A14-AB99-74A54310BEEEQ37533979-685E741E-20FA-4EA1-BDB0-A6C07229DEB6Q37569592-0A84778E-E4E0-4361-A0A4-452DD1409DF8Q38231425-F6E4165C-C599-461C-8523-6A1B5280231CQ38865531-9AFD386A-25D8-4C30-8545-F8B7C46BE1EEQ38880464-1A9D2774-FF6B-46A0-ACE9-1C1BF80BDB93Q40046503-4C0964B9-F209-4105-BF5F-E0678924FCBFQ42763446-01818FE1-B2BA-4A5C-B98E-8A22778BDEDEQ43299843-E53237BC-A795-4875-A6AC-8B72FB8AE9CCQ46104285-DBCC29BE-FA4C-47F2-9D49-707D12E144AEQ46104286-84F26D7F-3BB8-49EC-A7B5-3E777605B3FAQ46104291-76A028A6-9822-4CFF-9E9E-E64D757E48F5Q48063226-C2228109-7DC6-4DFE-B057-6A08A61C9CACQ48502792-1D47B3CF-71C1-4E27-9026-6D6761C8BBD9Q49401023-673749E8-6AC0-4E95-92C8-ACB39EC020C2Q52737455-032B0716-728B-4113-8C23-DEB811F72BD1Q58046411-EF96C999-B8CB-48FF-BACF-6D63BE091CEFQ58772916-A276C19E-3D59-40F8-B677-56457D0F21D1
P2860
Identification of the amino-acetonitrile derivative monepantel (AAD 1566) as a new anthelmintic drug development candidate.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Identification of the amino-ac ...... ic drug development candidate.
@ast
Identification of the amino-ac ...... ic drug development candidate.
@en
type
label
Identification of the amino-ac ...... ic drug development candidate.
@ast
Identification of the amino-ac ...... ic drug development candidate.
@en
prefLabel
Identification of the amino-ac ...... ic drug development candidate.
@ast
Identification of the amino-ac ...... ic drug development candidate.
@en
P2093
P2860
P1476
Identification of the amino-ac ...... ic drug development candidate.
@en
P2093
B C Hosking
F Schroeder
R Kaminsky
S Schorderet Weber
P2860
P2888
P304
P356
10.1007/S00436-008-1080-7
P577
2008-07-02T00:00:00Z