Transcriptional activation of homologous and heterologous genes by the hepatitis B virus X gene product in cells permissive for viral replication
about
Cloning and characterization of a novel hepatitis B virus x binding protein that inhibits viral replication.Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex.The enigmatic X gene of hepatitis B virusRFX1 is identical to enhancer factor C and functions as a transactivator of the hepatitis B virus enhancerProteasome complex as a potential cellular target of hepatitis B virus X proteinX region mutations of hepatitis B virus related to clinical severityGenetic variation of occult hepatitis B virus infectionHepatitis B virus X protein stimulates viral genome replication via a DDB1-dependent pathway distinct from that leading to cell death.Trans-activation function of a 3' truncated X gene-cell fusion product from integrated hepatitis B virus DNA in chronic hepatitis tissuesDifferent regions of hepatitis B virus X protein are required for enhancement of bZip-mediated transactivation versus transrepression.Hepatitis B virus biology.Inhibition of cellular proteasome activities mediates HBX-independent hepatitis B virus replication in vivo.Altered proteolysis and global gene expression in hepatitis B virus X transgenic mouse liver.The hepatitis B virus X protein targets the basic region-leucine zipper domain of CREB.pX, the HBV-encoded coactivator, suppresses the phenotypes of TBP and TAFII250 mutantsHepatitis B virus infection and primary hepatocellular carcinoma.The Tudor domain protein Spindlin1 is involved in intrinsic antiviral defense against incoming hepatitis B Virus and herpes simplex virus type 1Hepatitis B virus X antigen in the pathogenesis of chronic infections and the development of hepatocellular carcinoma.Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascadeA new hepadnavirus endemic in arctic ground squirrels in Alaska.Interaction of the UV-damaged DNA-binding protein with hepatitis B virus X protein is conserved among mammalian hepadnaviruses and restricted to transactivation-proficient X-insertion mutantsX-deficient woodchuck hepatitis virus mutants behave like attenuated viruses and induce protective immunity in vivo.Woodchuck hepatitis virus X protein is required for viral infection in vivo.The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks.Woodchuck hepatitis virus is a more efficient oncogenic agent than ground squirrel hepatitis virus in a common host.The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors.Regulation of transcription from the hepatitis B virus major surface antigen promoter by the Sp1 transcription factor.Hepatitis B virus X protein is not central to the viral life cycle in vitro.Alternate translation initiation on hepatitis B virus X mRNA produces multiple polypeptides that differentially transactivate class II and III promoters.Hepatitis B virus transactivator X protein is not tumorigenic in transgenic miceDifferentiation-specific transcriptional regulation of the hepatitis B virus large surface antigen gene in human hepatoma cell linesHepatitis B virus X protein produced in Escherichia coli is biologically functional.Activation of class I major histocompatibility complex gene expression by hepatitis B virus.A novel hepatitis B virus (HBV) genetic element with Rev response element-like properties that is essential for expression of HBV gene products.Expression and interactions of human adenovirus oncoproteins.HBx Gene Mutations in Hepatitis B Virus and Hepatocellular Carcinoma.Regulation of transforming growth factor-beta 1 expression by the hepatitis B virus (HBV) X transactivator. Role in HBV pathogenesis.Two core promotor mutations identified in a hepatitis B virus strain associated with fulminant hepatitis result in enhanced viral replication.Inhibition of cellular proteasome activities enhances hepadnavirus replication in an HBX-dependent manner.Frequent amplification of c-myc in ground squirrel liver tumors associated with past or ongoing infection with a hepadnavirus.
P2860
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P2860
Transcriptional activation of homologous and heterologous genes by the hepatitis B virus X gene product in cells permissive for viral replication
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Transcriptional activation of ...... rmissive for viral replication
@en
type
label
Transcriptional activation of ...... rmissive for viral replication
@en
prefLabel
Transcriptional activation of ...... rmissive for viral replication
@en
P2860
P1433
P1476
Transcriptional activation of ...... rmissive for viral replication
@en
P2093
P2860
P304
P407
P50
P577
1989-09-01T00:00:00Z