Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress.
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The role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancerComputational identification of a transiently open L1/S3 pocket for reactivation of mutant p53Role of Natural Radiosensitizers and Cancer Cell Radioresistance: An UpdateTargeting Oncogenic Mutant p53 for Cancer TherapyReactive Oxygen Species in Mesenchymal Stem Cell Aging: Implication to Lung DiseasesMechanisms of altered redox regulation in neurodegenerative diseases--focus on S--glutathionylationRedox control of microglial function: molecular mechanisms and functional significanceProtein glutathionylation in cardiovascular diseasesRegulation of signal transduction by reactive oxygen species in the cardiovascular systemRedox homeostasis: the linchpin in stem cell self-renewal and differentiationProtein Oxidative Modifications: Beneficial Roles in Disease and HealthMultiple functions of Nm23-H1 are regulated by oxido-reduction systemPosttranslational modification of human glyoxalase 1 indicates redox-dependent regulationS-glutathionylation: from molecular mechanisms to health outcomesMAOA-a novel decision maker of apoptosis and autophagy in hormone refractory neuroendocrine prostate cancer cells.Glutathionylation of the pro-apoptotic protein p53 in Alzheimer's disease brain: implications for AD pathogenesis.Inhibition of glutathione synthesis distinctly alters mitochondrial and cytosolic redox poiseCys-141 glutathionylation of human p53: Studies using specific polyclonal antibodies in cancer samples and cell lines.The NADPH oxidases NOX4 and DUOX2 regulate cell cycle entry via a p53-dependent pathway.Redox control systems in the nucleus: mechanisms and functions.Targeted quantitation of site-specific cysteine oxidation in endogenous proteins using a differential alkylation and multiple reaction monitoring mass spectrometry approachNew insights into the link between DNA damage and apoptosis.Stem cells and the impact of ROS signaling.Cysteine-mediated redox signaling: chemistry, biology, and tools for discoveryReversible and irreversible protein glutathionylation: biological and clinical aspects.Protein S-glutathiolation: redox-sensitive regulation of protein function.Corticotropin-Releasing Factor Receptor-1 Antagonism Reduces Oxidative Damage in an Alzheimer’s Disease Transgenic Mouse Model.Manganese porphyrin, MnTE-2-PyP5+, Acts as a pro-oxidant to potentiate glucocorticoid-induced apoptosis in lymphoma cells.Glutathione synthesis and its role in redox signaling.Individual interferon regulatory factor-3 thiol residues are not critical for its activation following virus infection.Metabolic regulation of oxygen and redox homeostasis by p53: lessons from evolutionary biology?A role for DNA-mediated charge transport in regulating p53: Oxidation of the DNA-bound protein from a distance.In vivo tagging and characterization of S-glutathionylated proteins by a chemoenzymatic method.Reduced glutathione: a radioprotector or a modulator of DNA-repair activity?Degradation of NF-κB, p53 and other regulatory redox-sensitive proteins by thiol-conjugating and -nitrosylating drugs in human tumor cells.Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism.Cysteine S-Glutathionylation Promotes Stability and Activation of the Hippo Downstream Effector Transcriptional Co-activator with PDZ-binding Motif (TAZ).Redox regulation of multidrug resistance in cancer chemotherapy: molecular mechanisms and therapeutic opportunitiesPhenylethyl isothiocyanate reverses cisplatin resistance in biliary tract cancer cells via glutathionylation-dependent degradation of Mcl-1The chemistry of cell signaling by reactive oxygen and nitrogen species and 4-hydroxynonenal.
P2860
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P2860
Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Human p53 is inhibited by glut ...... omain during oxidative stress.
@en
type
label
Human p53 is inhibited by glut ...... omain during oxidative stress.
@en
prefLabel
Human p53 is inhibited by glut ...... omain during oxidative stress.
@en
P2093
P2860
P356
P1433
P1476
Human p53 is inhibited by glut ...... domain during oxidative stress
@en
P2093
Catalin E Doneanu
Chinavenmeni S Velu
Nagarajan Pattabiraman
Suryakant K Niture
P2860
P304
P356
10.1021/BI700425Y
P407
P577
2007-06-08T00:00:00Z