Exendin-4 stimulation of cyclin A2 in beta-cell proliferation.
about
CREB is activated by muscle injury and promotes muscle regenerationTcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell linePancreatic β-cell proliferation in obesity.The negative cell cycle regulators, p27(Kip1), p18(Ink4c), and GSK-3, play critical role in maintaining quiescence of adult human pancreatic β-cells and restrict their ability to proliferate.FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation.Repurposing cAMP-modulating medications to promote β-cell replication.Snapin mediates incretin action and augments glucose-dependent insulin secretionIncreasing β-cell mass requires additional stimulation for adaptation to secretory demandActivation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activationPKA Enhances the Acute Insulin Response Leading to the Restoration of Glucose Control.Skp2 is required for incretin hormone-mediated β-cell proliferationA noncytolytic antibody-like extendin-4-IgG4 fusion protein as a long-acting potential anti-diabetic agent.Exendin-4 increases histone acetylase activity and reverses epigenetic modifications that silence Pdx1 in the intrauterine growth retarded rat.A simple matter of life and death-the trials of postnatal Beta-cell mass regulationChREBP mediates glucose-stimulated pancreatic β-cell proliferation.Human β-cell proliferation and intracellular signaling: driving in the dark without a road map.Small molecule kaempferol modulates PDX-1 protein expression and subsequently promotes pancreatic β-cell survival and function via CREB.Early and Late G1/S Cyclins and Cdks Act Complementarily to Enhance Authentic Human β-Cell Proliferation and Expansion.iPSC-derived β cells model diabetes due to glucokinase deficiencyPancreatic β-cell response to increased metabolic demand and to pharmacologic secretagogues requires EPAC2AMinireview: Meeting the demand for insulin: molecular mechanisms of adaptive postnatal beta-cell mass expansionHuman β-cell proliferation and intracellular signaling part 2: still driving in the dark without a road map.Beta-cell protection and therapy for latent autoimmune diabetes in adults.Gastrointestinal hormones and the regulation of β-cell mass.The role of autophagy in endoplasmic reticulum stress-induced pancreatic β cell death.Latent autoimmune diabetes in the adults (LADA) in Asia: from pathogenesis and epidemiology to therapy.Glucagon-like peptide 1-potentiated insulin secretion and proliferation of pancreatic β-cells.New insights concerning the molecular basis for defective glucoregulation in soluble adenylyl cyclase knockout miceDiabetes mellitus--advances and challenges in human β-cell proliferation.Rb and p107 are required for alpha cell survival, beta cell cycle control and glucagon-like peptide-1 action.Exendin-4 promotes pancreatic β-cell proliferation via inhibiting the expression of Wnt5a.GLP-1 signalling compensates for impaired insulin signalling in regulating beta cell proliferation in βIRKO mice.Novel factors modulating human β-cell proliferation.Betacellulin ameliorates hyperglycemia in obese diabetic db/db mice.Stromal cell-derived factor-1 promotes survival of pancreatic beta cells by the stabilisation of beta-catenin and activation of transcription factor 7-like 2 (TCF7L2).Nupr1 deletion protects against glucose intolerance by increasing beta cell mass.Liraglutide Improves the Survival of INS-1 Cells by Promoting Macroautophagy.Developmentally regulated inhibition of cell cycle progression by glucocorticoids through repression of cyclin A transcription in primary osteoblast cultures.Menin and PRMT5 suppress GLP1 receptor transcript and PKA-mediated phosphorylation of FOXO1 and CREB.Enhanced Expression of the Key Mitosis Regulator Cyclin B1 Is Mediated by PDZ-Binding Kinase in Islets of Pregnant Mice.
P2860
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P2860
Exendin-4 stimulation of cyclin A2 in beta-cell proliferation.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Exendin-4 stimulation of cyclin A2 in beta-cell proliferation.
@en
type
label
Exendin-4 stimulation of cyclin A2 in beta-cell proliferation.
@en
prefLabel
Exendin-4 stimulation of cyclin A2 in beta-cell proliferation.
@en
P2093
P2860
P356
P1433
P1476
Exendin-4 stimulation of cyclin A2 in beta-cell proliferation.
@en
P2093
Benjamin D Kornfeld
Enhong Zhong
Fei-Fei Liu
Fredric E Wondisford
Mehboob A Hussain
Weston E Schreiber
Woo-Jin Song
P2860
P304
P356
10.2337/DB07-1541
P407
P577
2008-06-10T00:00:00Z