Advancements in the pathophysiology of Friedreich's Ataxia and new prospects for treatments.
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Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesIron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxiaTherapeutic developments in Friedreich ataxiaIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesMesenchymal stem cells restore frataxin expression and increase hydrogen peroxide scavenging enzymes in Friedreich ataxia fibroblastsFriedreich ataxia: molecular mechanisms, redox considerations, and therapeutic opportunities.A rapid, noninvasive immunoassay for frataxin: utility in assessment of Friedreich ataxiaIron-sulfur cluster biogenesis and human diseasemiR-210 targets iron-sulfur cluster scaffold homologue in human trophoblast cell lines: siderosis of interstitial trophoblasts as a novel pathology of preterm preeclampsia and small-for-gestational-age pregnancies.An AAV9 coding for frataxin clearly improved the symptoms and prolonged the life of Friedreich ataxia mouse modelsComplications associated with surgical repair of syndromic scoliosis.Hepatic Deficiency of Augmenter of Liver Regeneration Exacerbates Alcohol-Induced Liver Injury and Promotes Fibrosis in Mice.Lateral-flow immunoassay for the frataxin protein in Friedreich's ataxia patients and carriers.Metal attenuating therapies in neurodegenerative disease.DNA triplex structures in neurodegenerative disorder, Friedreich's ataxia.Redox- and non-redox-metal-induced formation of free radicals and their role in human disease.A Potential New Therapeutic Approach for Friedreich Ataxia: Induction of Frataxin Expression With TALE Proteins.Liver Growth Factor (LGF) Upregulates Frataxin Protein Expression and Reduces Oxidative Stress in Friedreich's Ataxia Transgenic Mice.Mesenchymal Stem Cell-Derived Factors Restore Function to Human Frataxin-Deficient Cells.Clinical manifestation and a new ISCU mutation in iron-sulphur cluster deficiency myopathy.Ironing out neurodegeneration: iron chelation for neuroprotectionQuantitative profiling and identification of differentially expressed plasma proteins in Friedreich's ataxia.Analysis of the visual system in Friedreich ataxia.Deletion of the GAA repeats from the human frataxin gene using the CRISPR-Cas9 system in YG8R-derived cells and mouse models of Friedreich ataxia.Friedreich's ataxia: clinical features, pathogenesis and management.Synthesis of frataxin genes by direct assembly of serial deoxyoligonucleotide primers and its expression in Escherichia coli
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Advancements in the pathophysiology of Friedreich's Ataxia and new prospects for treatments.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Advancements in the pathophysi ...... new prospects for treatments.
@en
type
label
Advancements in the pathophysi ...... new prospects for treatments.
@en
prefLabel
Advancements in the pathophysi ...... new prospects for treatments.
@en
P2093
P2860
P1476
Advancements in the pathophysi ...... d new prospects for treatments
@en
P2093
David R Lynch
Grazia Isaya
Martin B Delatycki
Michio Hirano
Nadege Carelle
Ngolela E Babady
Robert B Wilson
Robert D Wells
Tracey A Rouault
P2860
P356
10.1016/J.YMGME.2007.05.009
P577
2007-06-26T00:00:00Z