Evaluation of energy metabolism and calcium homeostasis in cells affected by Shwachman-Diamond syndrome.
about
SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention.Why is an energy metabolic defect the common outcome in BMFS?Uptake of polyphosphate microparticles in vitro (SaOS-2 and HUVEC cells) followed by an increase of the intracellular ATP pool size.Hypomorphic FANCA mutations correlate with mild mitochondrial and clinical phenotype in Fanconi anemia.Mutations in signal recognition particle SRP54 cause syndromic neutropenia with Shwachman-Diamond-like features.Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA.
P2860
Evaluation of energy metabolism and calcium homeostasis in cells affected by Shwachman-Diamond syndrome.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Evaluation of energy metabolis ...... by Shwachman-Diamond syndrome.
@en
type
label
Evaluation of energy metabolis ...... by Shwachman-Diamond syndrome.
@en
prefLabel
Evaluation of energy metabolis ...... by Shwachman-Diamond syndrome.
@en
P2093
P2860
P50
P356
P1433
P1476
Evaluation of energy metabolis ...... by Shwachman-Diamond syndrome.
@en
P2093
Carlo Dufour
Fabio Corsolini
Marco Cipolli
Paola Cuccarolo
P2860
P2888
P356
10.1038/SREP25441
P407
P50
P577
2016-05-05T00:00:00Z
P6179
1009792555