Unfolding, aggregation, and amyloid formation by the tetramerization domain from mutant p53 associated with lung cancer.
about
Potential roles for prions and protein-only inheritance in cancerAn intrinsically disordered region of the acetyltransferase p300 with similarity to prion-like domains plays a role in aggregationProtein structural robustness to mutations: an in silico investigation.Ligand binding and hydration in protein misfolding: insights from studies of prion and p53 tumor suppressor proteins.Cancer-associated p53 tetramerization domain mutants: quantitative analysis reveals a low threshold for tumor suppressor inactivationIntermolecular β-strand networks avoid hub residues and favor low interconnectedness: a potential protection mechanism against chain dissociation upon mutation.Regulation of p53 oligomerization by Ras superfamily protein RBEL1AMutant p53 aggregates into prion-like amyloid oligomers and fibrils: implications for cancer.Stability and structural recovery of the tetramerization domain of p53-R337H mutant induced by a designed templating ligand.Expanding the prion concept to cancer biology: dominant-negative effect of aggregates of mutant p53 tumour suppressorThe aggregation of mutant p53 produces prion-like properties in cancer.Role of p53 isoforms and aggregations in cancer.The (1-63) region of the p53 transactivation domain aggregates in vitro into cytotoxic amyloid assemblies.A fluid salt-bridging cluster and the stabilization of p53.NetCSSP: web application for predicting chameleon sequences and amyloid fibril formation.p53 Aggregates penetrate cells and induce the co-aggregation of intracellular p53.Self-aggregation and coaggregation of the p53 core fragment with its aggregation gatekeeper variant.Treating p53 Mutant Aggregation-Associated Cancer.p53 Isoforms and Their Implications in Cancer
P2860
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P2860
Unfolding, aggregation, and amyloid formation by the tetramerization domain from mutant p53 associated with lung cancer.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Unfolding, aggregation, and am ...... 3 associated with lung cancer.
@en
type
label
Unfolding, aggregation, and am ...... 3 associated with lung cancer.
@en
prefLabel
Unfolding, aggregation, and am ...... 3 associated with lung cancer.
@en
P2093
P2860
P356
P1433
P1476
Unfolding, aggregation, and am ...... 3 associated with lung cancer.
@en
P2093
Carl W Anderson
Ettore Appella
Kazuyasu Sakaguchi
Kohei Uosaki
Marc S Lewis
Satoru Takakusagi
Stewart R Durell
Yuichiro Higashimoto
Yuya Asanomi
P2860
P304
P356
10.1021/BI051192J
P407
P577
2006-02-01T00:00:00Z